FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Polr2A, Dcr-2
FlyBase ID
FBig0000095858
Interaction Network
Interactions Browser links
Polr2A network
Dcr-2 network
Reported Interactions
FBrf0209388-2.coIP.WB
Reference
Kavi and Birchler, 2009
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Polr2A 

RNA Pol II

bait
Dcr-2 

Dicer-2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Kavi and Birchler, 2009)
FBrf0216979-5.coIP.WB
Reference
Cernilogar et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Polr2A 

RNA Pol II

bait
Dcr-2 

DCR2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line nuclear extracts.

(Cernilogar et al., 2011)

RNase treatment did not disrupt observed interaction.

(Cernilogar et al., 2011)
FBrf0216979-6.coIP.WB
Reference
Cernilogar et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Dcr-2 

DCR2

bait
Polr2A 

RNA Pol II

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line nuclear extracts.

(Cernilogar et al., 2011)

Compared with general transcription factors, the amount of RpII215 protein interacting with Dcr-2 protein appeared to be in the same range as for the Tbp (TATA-binding) protein.

(Cernilogar et al., 2011)

RNase treatment did not disrupt observed interaction.

(Cernilogar et al., 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)