FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
p53, Su(var)2-10
FlyBase ID
FBig0000096247
Interaction Network
Interactions Browser links
p53 network
Su(var)2-10 network
Reported Interactions
FBrf0216737-3.Y2H
Reference
Pardi et al., 2011
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
p53 

Dmp53

bait
Su(var)2-10 

PIAS

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryonic cDNA library.

(Pardi et al., 2011)

Two-hybrid system: yeast LexA/VP16.

(Pardi et al., 2011)
FBrf0216737-6.PD.A
Reference
Pardi et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
p53 

Dmp53

bait

GST pull down

Su(var)2-10 

PIAS

prey

[3]H label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cloned reagents; interaction in solution.

(Pardi et al., 2011)
FBrf0216737-9.Y2H
Reference
Pardi et al., 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
p53 

Dmp53

bait
p53 
Su(var)2-10 

PIAS

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
p53 
C- terminal region
sufficient binding region
aa 277-385
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Prey was cloned reagent (previously isolated).

(Pardi et al., 2011)

Two-hybrid system: yeast LexA/VP16.

(Pardi et al., 2011)

K302R modification of aa 302 (within a canonical SUMO acceptor site) has no affect upon this interaction.

(Pardi et al., 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)