FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Syx13, Vamp7
FlyBase ID
FBig0000097029
Interaction Network
Interactions Browser links
Syx13 network
Vamp7 network
Reported Interactions
FBrf0218395-2519.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Vamp7 
unspecified role
Vamp7 
unspecified role
Vamp7 
unspecified role
Syx13 
unspecified role
Syx13 
unspecified role
Syx13 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 226.77410

FBrf0237566-2.coIP.WB
Reference
Csizmadia et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Syx13 

Syx13

bait

FLAG tag

Vamp7 

Vamp7

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Csizmadia et al., 2018)

The Syx13-Vamp7 interaction is weak. The amount of Vamp7 that is coprecipitated with Syx13 is greatly increased if Snap29 is coexpressed.

(Csizmadia et al., 2018)
FBrf0258740-1.PD.MW
Reference
Szenci et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Syx13 

Syntaxin13

bait

GST tag

Syx13 
Vamp7 

Vamp7

prey

MBP tag

Vamp7 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Syx13 
SNARE Qa domain
sufficient binding region
unspecified

coordinates relative to Syx13-PA

Vamp7 
SNARE R domain
sufficient binding region
unspecified

coordinates relative to Vamp7-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait and prey produced as recombinant fusion proteins in bacterial system.

(Szenci et al., 2024)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)