FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
sqd, osk
FlyBase ID
FBig0000097088
Interaction Network
Interactions Browser links
sqd network
osk network
Reported Interactions
FBrf0191561-1.XL.IP.A
Reference
Norvell et al., 2005
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sqd 

sqd synonym

bait
osk 

osk synonym

prey

[32]P label

osk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
osk 
3-prime UTR
sufficient binding region
unspecified
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced and labeled by in vitro transcription; prey derived from wild-type adult female ovary extract.

(Norvell et al., 2005)
FBrf0218722-22.coIP.PCR
Reference
McDermott et al., 2012
Description
physical association
Assay
Collection
Source/Stage
ovary / adult stagefemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sqd 

Sqd

bait

GFP tag

osk 

osk

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult ovary of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(McDermott et al., 2012)
FBrf0222280-6.coIP.PCR
Reference
McDermott and Davis, 2013
Description
physical association
Assay
Collection
Source/Stage
ovary / adult stagefemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sqd 

Sqd

bait

GFP tag

osk 

oskar

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

sqd interacts with grk, osk and bcd RNA, but not nos or hb RNA.

(McDermott and Davis, 2013)

Source was adult female ovary of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(McDermott and Davis, 2013)

Positive control.

(McDermott and Davis, 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)