FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\sqd
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General Information
Symbol
Dmel\sqd
Species
D. melanogaster
Name
squid
Annotation Symbol
CG16901
Feature Type
protein_coding_gene
FlyBase ID
FBgn0263396
Gene Model Status
Current
Stock Availability
18 publicly available
Gene Summary
squid (sqd) encodes a member of the hnRNPA family of RNA binding proteins. It is involved in the localization and translational regulation of grk mRNA in oogenesis. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

hrp40, l(3)j4B4, l(3)EP3631, hnRNP A, RRM3

Key Links
Genomic Location
Cytogenetic map
87F5-87F6
Sequence location
Recombination map
3-54
RefSeq locus
NT_033777 REGION:13634862..13646304
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (30 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables mRNA 3'-UTR binding
traceable author statement
(Johnstone and Lasko, 2001, Cooperstock and Lipshitz, 1997)
enables nucleic acid binding
inferred from electronic annotation with InterPro:IPR035979
(InterPro Project Members, 2004-)
enables RNA binding
inferred from biological aspect of ancestor with PANTHER:PTN002689978
(GO Reference Genome Project, 2011-)
inferred from electronic annotation with InterPro:IPR000504
(InterPro Project Members, 2004-)
Biological Process (19 terms)
Terms Based on Experimental Evidence (12 terms)
CV Term
Evidence
References
involved_in dorsal/ventral axis specification, ovarian follicular epithelium
inferred from mutant phenotype
(Kelley, 1993)
involved_in dorsal/ventral pattern formation
inferred from mutant phenotype
(Clouse et al., 2008)
involved_in follicle cell of egg chamber migration
inferred from mutant phenotype
(Kelley, 1993)
involved_in germarium-derived egg chamber formation
inferred from mutant phenotype
(Steinhauer and Kalderon, 2005)
involved_in negative regulation of RNA splicing
inferred from mutant phenotype
(Ji and Tulin, 2009)
involved_in oocyte anterior/posterior axis specification
inferred from mutant phenotype
(Steinhauer and Kalderon, 2005)
involved_in oocyte localization involved in germarium-derived egg chamber formation
inferred from mutant phenotype
(Steinhauer and Kalderon, 2005)
involved_in oocyte microtubule cytoskeleton organization
inferred from mutant phenotype
(Steinhauer and Kalderon, 2005)
involved_in oogenesis
inferred from mutant phenotype
(Steinhauer and Kalderon, 2005)
involved_in pole plasm mRNA localization
inferred from mutant phenotype
(Herpers and Rabouille, 2004)
involved_in pole plasm oskar mRNA localization
inferred from expression pattern
(Norvell et al., 2005)
involved_in regulation of alternative mRNA splicing, via spliceosome
inferred from high throughput mutant phenotype
(Park et al., 2004)
Terms Based on Predictions or Assertions (9 terms)
CV Term
Evidence
References
involved_in dorsal/ventral pattern formation
traceable author statement
(Farina and Singer, 2002, Cooperstock and Lipshitz, 1997)
involved_in intracellular mRNA localization
non-traceable author statement
(Tekotte and Davis, 2002)
traceable author statement
(Farina and Singer, 2002, Johnstone and Lasko, 2001, Cooperstock and Lipshitz, 1997)
involved_in mRNA export from nucleus
non-traceable author statement
(Tekotte and Davis, 2002)
involved_in mRNA splicing, via spliceosome
inferred by curator from GO:0071011,GO:0071013
(Herold et al., 2009)
involved_in negative regulation of translation
traceable author statement
(Cooperstock and Lipshitz, 1997)
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
traceable author statement
(Farina and Singer, 2002)
involved_in oogenesis
traceable author statement
(Farina and Singer, 2002)
involved_in regulation of gene expression
inferred from biological aspect of ancestor with PANTHER:PTN002689978
(GO Reference Genome Project, 2011-)
involved_in RNA export from nucleus
traceable author statement
(Cooperstock and Lipshitz, 1997)
Cellular Component (8 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
part_of catalytic step 2 spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
located_in chromatin
inferred from direct assay
(Prasanth et al., 2000)
located_in nucleus
inferred from direct assay
(Prasanth et al., 2000, Matunis et al., 1992)
inferred from high throughput direct assay
(Lye et al., 2014)
located_in omega speckle
inferred from direct assay
(Prasanth et al., 2000)
located_in polytene chromosome puff
inferred from direct assay
(Ji and Tulin, 2009, Matunis et al., 1992)
part_of precatalytic spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
is_active_in chromatin
inferred from biological aspect of ancestor with PANTHER:PTN002689978
(GO Reference Genome Project, 2011-)
located_in cytoplasm
traceable author statement
(Johnstone and Lasko, 2001)
is_active_in nucleoplasm
inferred from biological aspect of ancestor with PANTHER:PTN002689978
(GO Reference Genome Project, 2011-)
located_in nucleus
traceable author statement
(Johnstone and Lasko, 2001, Cooperstock and Lipshitz, 1997)
inferred by curator from GO:0000381
(Park et al., 2004)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
squid (sqd) encodes a member of the hnRNPA family of RNA binding proteins. It is involved in the localization and translational regulation of grk mRNA in oogenesis. [Date last reviewed: 2019-03-14]
Gene Group (FlyBase)
SPLICEOSOME COMPLEX A -
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex A, the pre-spliceosome, is composed of U1 and U2 snRNPs and proteins involved in recognition of the 5' splice site and branch point. (Adapted from PMID:24452469 and PMID:23118483).
Protein Function (UniProtKB)
Component of ribonucleosomes (PubMed:7684991). Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle (PubMed:7684991). At least one of the isoforms is essential in somatic tissues (PubMed:7684991). Interacts with grk mRNA (via 3' UTR) and involved in its localization to the dorsal anterior region of the oocyte during dorsal-ventral axis determination; may function as a ribonuclear protein complex together with otu and Hrb27C (PubMed:10197986, PubMed:15056611). Required for polytene chromosome dispersal in nurse cells during oogenesis; nuclear isoforms play a greater role in this than cytoplasmic isoforms (PubMed:15056611).
(UniProt, Q08473)
Summary (Interactive Fly)

RNA-binding protein, hnRNP D homolog - Gurken mRNA localization and translation are coupled by an interaction between Sqd and the translational repressor protein Bruno - Squid promotes apical cytoplasmic transport and localization of Fushi tarazu transcripts

Gene Model and Products
Number of Transcripts
5
Number of Unique Polypeptides
4

Please see the JBrowse view of Dmel\sqd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q08473)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.47

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
sqd-RA
FBtr0082854
NM_169529
5551
321
sqd-RB
FBtr0082855
NM_169528
2115
344
sqd-RC
FBtr0082856
NM_143952
2239
308
sqd-RD
FBtr0082857
NM_206481
1983
178
sqd-RE
FBtr0309094
NM_001260159
2844
308
Additional Transcript Data and Comments
Reported size (kB)

4.8, 3.5, 2.3, 1.9, 1.7, 1.5 (northern blot)

(Kelley, 1993)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
sqd-PA
FBpp0082319
35.0
321
6.54
NP_731826
AAF54964
sqd-PB
FBpp0082320
36.2
344
7.62
Q08473
NP_731825
AAF54963
sqd-PC
FBpp0082321
33.1
308
6.96
A0A0B4K6U6
NP_652209
AAN13570
sqd-PD
FBpp0089309
18.3
178
9.97
NP_996203
AAS65146
sqd-PE
FBpp0301102
33.1
308
6.96
A0A0B4K6U6
NP_001247088
AFH06406
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

308 aa isoforms: sqd-PC, sqd-PE
Additional Polypeptide Data and Comments
Reported size (kDa)

321, 308 (aa)

(Kelley, 1993)

40 (kD observed)

(Matunis et al., 1992)

345, 321 (aa); 40 (kD observed); 36, 35 (kD predicted)

(Matunis et al., 1992)
Comments
External Data
Subunit Structure (UniProtKB)

Interacts with bru1/Bruno; the interaction is direct but weak, and may play a role in regulation of grk mRNA localization and translation.

(UniProt, Q08473)
Domain

Possesses 2 putative nuclear-localization domains, a M9 motif found only in isoform B (sqdS) and a M9-like motif found in all isoforms described (Probable). These may mediate interaction with Tnpo/Transportin and Transportin-dependent nuclear localization (PubMed:10197986).

(UniProt, Q08473)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sqd using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.18

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | intense | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
organism | intense | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
organism | intense | ubiquitous
(Fisher et al., 2012)
embryonic stage 11 -- 12
organism | intense | ubiquitous
(Fisher et al., 2012)
embryonic stage 13 -- 16
organism | intense | ubiquitous
(Fisher et al., 2012)
embryonic/larval midgut
(Fisher et al., 2012)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | female
(Kelley, 1993)
oogenesis & adult stage | female
ovary
(Kelley, 1993)
RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
oogenesis stage S8 -- S14 & adult stage | female
egg chamber
(Van Buskirk and Schupbach, 2002)
oogenesis
egg chamber
(Van Buskirk and Schupbach, 2002)
Additional Descriptive Data

Isoform-specific expression patterns are observed. Sex-specific expression of alternative transcripts observed.

(Telonis-Scott et al., 2009)

1.5kb sqd transcripts are expressed predominantly in ovaries.

(Kelley, 1993)

2.3kb sqd transcripts are expressed predominantly in non-ovarian tissues.

(Kelley, 1993)

1.9kb sqd transcripts are expressed predominantly in ovaries.

(Kelley, 1993)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
oogenesis
oocyte
(Cáceres and Nilson, 2009)
nurse cell
(Cáceres and Nilson, 2009)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | female
ovary
(Goodrich et al., 2004)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
part_of catalytic step 2 spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
located_in chromatin
inferred from direct assay
(Prasanth et al., 2000)
located_in nucleus
inferred from direct assay
(Prasanth et al., 2000, Matunis et al., 1992)
inferred from high throughput direct assay
(Lye et al., 2014)
located_in omega speckle
inferred from direct assay
(Prasanth et al., 2000)
located_in polytene chromosome puff
inferred from direct assay
(Ji and Tulin, 2009, Matunis et al., 1992)
part_of precatalytic spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\sqd in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 35 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 16 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of sqd
Transgenic constructs containing regulatory region of sqd
Aberrations (Deficiencies and Duplications) ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal, with Scer\GAL4Mef2.PR
lethal (with Df(3R)l26c)
lethal (with Df(3R)urd)
lethal | recessive
lethal - all die before end of pupal stage, with Scer\GAL4pnr-MD237
lethal - all die during embryonic stage | maternal effect
partially lethal
partially lethal - majority die (with Df(3R)urd)
partially lethal - majority die (with sqdix50)
partially lethal - majority die (with sqdix77)
partially lethal - majority die (with sqdj4B4)
viable
viable, with Scer\GAL4tin.CΔ4
Sterility
Allele
female sterile
female sterile, with Scer\GAL4VP16.otu
female sterile (with sqd1)
female sterile (with sqdix50)
female sterile (with sqdix77)
female sterile | recessive
semi-sterile | recessive
Other Phenotypes
Allele
increased occurrence of cell division | spermatogenesis, with Scer\GAL4VP16.nanos.UTR
short lived | heat sensitive, with Scer\GAL4tin.CΔ4
some die during embryonic stage | maternal effect
some die during pupal stage, with Scer\GAL4pnr-MD237
visible, with Scer\GAL4GMR.PF
Phenotype manifest in
Allele
border follicle cell | germline clone
centripetal follicle cell | germline clone
cyst cell of ovary | germline clone
dorsal appendage
dorsal appendage (with sqd1)
dorsal appendage (with sqdK12)
dorsal appendage | germline clone
dorsal appendage | maternal effect
egg
egg (with sqd1)
egg (with sqdK12)
egg | germline clone
egg | maternal effect | ventral
egg chamber | germline clone
egg chorion
egg chorion (with sqd1)
egg chorion (with sqdK12)
egg chorion | dorsal
egg operculum (with sqd1)
egg operculum (with sqdK12)
filzkorper | maternal effect
follicle cell | germline clone
interommatidial bristle, with Scer\GAL4GMR.PF
microtubule organizing center & oocyte | germ-line clone
nurse cell & nuclear chromosome
nurse cell | germline clone
oocyte
oocyte (with Df(3R)urd)
oocyte (with sqd1)
oocyte (with sqdix50)
oocyte (with sqdix77)
oocyte (with sqdj4B4)
oocyte & microtubule | germ-line clone
oocyte | germline clone
ovariole | germline clone
spermatogonium, with Scer\GAL4ptc-559.1
stalk follicle cell | germline clone
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (96)
Hsap\HNRNPD
11 of 14
Yes
Yes
Hsap\HNRNPAB
9 of 14
No
Yes
Hsap\HNRNPDL
9 of 14
No
Yes
4  
Hsap\DAZAP1
2 of 14
No
No
Hsap\MSI1
2 of 14
No
No
1  
Hsap\MSI2
2 of 14
No
No
1  
Hsap\RBM24
2 of 14
No
Yes
Hsap\BOLL
1 of 14
No
No
2  
Hsap\CELF1
1 of 14
No
No
3  
Hsap\CELF2
1 of 14
No
No
Hsap\CELF3
1 of 14
No
No
Hsap\CELF4
1 of 14
No
No
Hsap\CELF5
1 of 14
No
No
1  
Hsap\CELF6
1 of 14
No
No
Hsap\CIRBP
1 of 14
No
No
Hsap\CPEB1
1 of 14
No
No
Hsap\CPEB2
1 of 14
No
No
1  
Hsap\CPEB3
1 of 14
No
No
Hsap\CPEB4
1 of 14
No
No
Hsap\CSTF2
1 of 14
No
No
Hsap\CSTF2T
1 of 14
No
No
Hsap\DAZ1
1 of 14
No
No
Hsap\DAZ4
1 of 14
No
No
Hsap\ELAVL1
1 of 14
No
No
3  
Hsap\ELAVL2
1 of 14
No
No
2  
Hsap\ELAVL3
1 of 14
No
No
3  
Hsap\ELAVL4
1 of 14
No
No
2  
Hsap\FUS
1 of 14
No
No
83  
Hsap\HNRNPA0
1 of 14
No
No
Hsap\HNRNPA1
1 of 14
No
No
5  
Hsap\HNRNPA1L2
1 of 14
No
No
Hsap\HNRNPA1P48
1 of 14
No
No
Hsap\HNRNPA2B1
1 of 14
No
No
13  
Hsap\HNRNPA3
1 of 14
No
No
2  
Hsap\NCBP2
1 of 14
No
No
Hsap\NCL
1 of 14
No
No
Hsap\PABPC1
1 of 14
No
No
2  
Hsap\PABPC1L
1 of 14
No
No
Hsap\PABPC3
1 of 14
No
No
1  
Hsap\PABPC4
1 of 14
No
No
1  
Hsap\PABPC4L
1 of 14
No
No
Hsap\PABPC5
1 of 14
No
No
Hsap\PABPN1
1 of 14
No
No
8  
Hsap\PABPN1L
1 of 14
No
No
Hsap\PPIL4
1 of 14
No
No
Hsap\PSPC1
1 of 14
No
No
1  
Hsap\PUF60
1 of 14
No
No
Hsap\RBFOX1
1 of 14
No
No
2  
Hsap\RBFOX2
1 of 14
No
No
Hsap\RBFOX3
1 of 14
No
No
Hsap\RBM3
1 of 14
No
No
Hsap\RBM4B
1 of 14
No
No
Hsap\RBM4
1 of 14
No
No
1  
Hsap\RBM7
1 of 14
No
No
Hsap\RBM11
1 of 14
No
No
Hsap\RBM19
1 of 14
No
No
1  
Hsap\RBM23
1 of 14
No
No
Hsap\RBM28
1 of 14
No
No
1  
Hsap\RBM34
1 of 14
No
No
Hsap\RBM38
1 of 14
No
No
Hsap\RBM39
1 of 14
No
No
Hsap\RBM42
1 of 14
No
No
Hsap\RBM45
1 of 14
No
No
Hsap\RBMS1
1 of 14
No
No
Hsap\RBMS2
1 of 14
No
No
1  
Hsap\RBMS3
1 of 14
No
No
Hsap\RBMXL3
1 of 14
No
Yes
Hsap\RBMY1A1
1 of 14
No
No
Hsap\RBMY1B
1 of 14
No
No
Hsap\RBMY1C
1 of 14
No
Yes
Hsap\RBMY1D
1 of 14
No
No
Hsap\RBMY1E
1 of 14
No
Yes
Hsap\RBMY1F
1 of 14
No
Yes
Hsap\RBMY1J
1 of 14
No
No
Hsap\SF3B4
1 of 14
No
No
Hsap\SF3B6
1 of 14
No
No
Hsap\SFPQ
1 of 14
No
No
3  
Hsap\SLIRP
1 of 14
No
No
1  
Hsap\SNRNP35
1 of 14
No
No
Hsap\SNRPA
1 of 14
No
No
1  
Hsap\SNRPB2
1 of 14
No
No
2  
Hsap\SPEN
1 of 14
No
No
Hsap\SREK1
1 of 14
No
No
1  
Hsap\SRSF1
1 of 14
No
No
20  
Hsap\SRSF2
1 of 14
No
No
0  
Hsap\SRSF8
1 of 14
No
No
Hsap\SRSF10
1 of 14
No
No
Hsap\SRSF12
1 of 14
No
No
Hsap\SYNCRIP
1 of 14
No
No
1  
Hsap\TARDBP
1 of 14
No
No
144  
Hsap\TIA1
1 of 14
No
No
Hsap\TIAL1
1 of 14
No
No
1  
Hsap\TRA2A
1 of 14
No
No
2  
Hsap\TRA2B
1 of 14
No
No
1  
Hsap\U2AF2
1 of 14
No
No
4  
Hsap\ZCRB1
1 of 14
No
Yes
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (56)
Rnor\Hnrnpd
11 of 14
Yes
Yes
Rnor\Hnrnpab
10 of 14
No
Yes
Rnor\Hnrnpdl
10 of 14
No
Yes
Rnor\Rbm31y
5 of 14
No
Yes
Rnor\Dazap1
2 of 14
No
No
Rnor\Msi1
2 of 14
No
No
Rnor\Celf1
1 of 14
No
No
Rnor\Celf2
1 of 14
No
No
Rnor\Celf5
1 of 14
No
No
Rnor\Celf6
1 of 14
No
No
Rnor\Cpeb1
1 of 14
No
No
Rnor\Cpeb2
1 of 14
No
No
Rnor\Cpeb3
1 of 14
No
No
Rnor\Cpeb4
1 of 14
No
No
Rnor\Cstf2t
1 of 14
No
No
Rnor\Elavl2
1 of 14
No
No
Rnor\Elavl4
1 of 14
No
No
Rnor\Hnrnpa1
1 of 14
No
No
Rnor\Hnrnpa2b1
1 of 14
No
No
Rnor\Hnrnpa3
1 of 14
No
No
Rnor\LOC681410
1 of 14
No
No
Rnor\LOC100911361
1 of 14
No
No
Rnor\Msi2
1 of 14
No
No
Rnor\Ncbp2
1 of 14
No
No
Rnor\Ncl
1 of 14
No
No
Rnor\Pabpc1l
1 of 14
No
No
Rnor\Pabpc1
1 of 14
No
No
Rnor\Pabpc4l
1 of 14
No
No
Rnor\Pabpc6
1 of 14
No
No
Rnor\Pabpn1l
1 of 14
No
No
Rnor\Pabpn1
1 of 14
No
No
Rnor\Ppil4
1 of 14
No
No
Rnor\Pspc1
1 of 14
No
No
Rnor\Puf60
1 of 14
No
No
Rnor\Rbfox2
1 of 14
No
No
Rnor\Rbfox3
1 of 14
No
No
Rnor\Rbm3
1 of 14
No
No
Rnor\Rbm19
1 of 14
No
No
Rnor\Rbm24
1 of 14
No
Yes
Rnor\Rbm34
1 of 14
No
No
Rnor\Rbm38
1 of 14
No
Yes
Rnor\Rbmx
1 of 14
No
No
Rnor\Sf3b6
1 of 14
No
No
Rnor\Slirp
1 of 14
No
No
Rnor\Snrpa
1 of 14
No
No
Rnor\Spen
1 of 14
No
No
Rnor\Srsf1
1 of 14
No
No
Rnor\Srsf8
1 of 14
No
No
Rnor\Srsf12
1 of 14
No
No
Rnor\Syncrip
1 of 14
No
No
Rnor\Tardbp
1 of 14
No
No
Rnor\Tia1
1 of 14
No
No
Rnor\Tial1
1 of 14
No
No
Rnor\Tra2a
1 of 14
No
No
Rnor\Tra2b
1 of 14
No
No
Rnor\Zcrb1
1 of 14
No
Yes
Mus musculus (laboratory mouse) (62)
Mmus\Hnrnpab
10 of 14
Yes
Yes
Mmus\Hnrnpdl
10 of 14
Yes
Yes
Mmus\Hnrnpd
10 of 14
Yes
Yes
Mmus\Gm21379
5 of 14
No
Yes
Mmus\Rbm31y
5 of 14
No
Yes
Mmus\Dazap1
2 of 14
No
No
Mmus\Msi1
2 of 14
No
No
Mmus\Msi2
2 of 14
No
No
Mmus\Rbm24
2 of 14
No
Yes
Mmus\4930595M18Rik
1 of 14
No
No
Mmus\Celf1
1 of 14
No
No
Mmus\Celf2
1 of 14
No
No
Mmus\Celf3
1 of 14
No
No
Mmus\Celf4
1 of 14
No
No
Mmus\Celf5
1 of 14
No
No
Mmus\Celf6
1 of 14
No
No
Mmus\Cpeb1
1 of 14
No
No
Mmus\Cpeb2
1 of 14
No
No
0  
Mmus\Cpeb3
1 of 14
No
No
Mmus\Cpeb4
1 of 14
No
No
Mmus\Cstf2
1 of 14
No
No
Mmus\Cstf2t
1 of 14
No
No
Mmus\Elavl2
1 of 14
No
No
Mmus\Elavl4
1 of 14
No
No
Mmus\Gm3376
1 of 14
No
No
Mmus\Gm4916
1 of 14
No
Yes
Mmus\Hnrnpa0
1 of 14
No
No
Mmus\Hnrnpa1
1 of 14
No
No
Mmus\Hnrnpa2b1
1 of 14
No
No
Mmus\Hnrnpa3
1 of 14
No
No
Mmus\Ncbp2
1 of 14
No
No
Mmus\Ncl
1 of 14
No
No
Mmus\Pabpc1l
1 of 14
No
No
Mmus\Pabpc1
1 of 14
No
No
Mmus\Pabpc4l
1 of 14
No
No
Mmus\Pabpc5
1 of 14
No
No
Mmus\Pabpc6
1 of 14
No
No
Mmus\Pabpn1l
1 of 14
No
No
Mmus\Pabpn1
1 of 14
No
No
Mmus\Ppil4
1 of 14
No
No
Mmus\Pspc1
1 of 14
No
No
Mmus\Puf60
1 of 14
No
No
Mmus\Rbfox2
1 of 14
No
No
Mmus\Rbfox3
1 of 14
No
No
Mmus\Rbm19
1 of 14
No
No
Mmus\Rbm28
1 of 14
No
No
Mmus\Rbm34
1 of 14
No
No
Mmus\Rbm38
1 of 14
No
Yes
Mmus\Rbms1
1 of 14
No
No
Mmus\Rbmx
1 of 14
No
No
Mmus\Sf3b6
1 of 14
No
No
Mmus\Slirp
1 of 14
No
No
Mmus\Snrnp35
1 of 14
No
No
Mmus\Snrpa
1 of 14
No
No
Mmus\Srsf1
1 of 14
No
No
Mmus\Syncrip
1 of 14
No
No
Mmus\Tardbp
1 of 14
No
No
Mmus\Tia1
1 of 14
No
No
Mmus\Tial1
1 of 14
No
No
Mmus\Tra2a
1 of 14
No
No
Mmus\Tra2b
1 of 14
No
No
Mmus\Zcrb1
1 of 14
No
Yes
Xenopus tropicalis (Western clawed frog) (45)
Xtro\hnrnpab
8 of 13
Yes
Yes
Xtro\hnrnpdl
8 of 13
Yes
Yes
Xtro\hnrnpd
8 of 13
Yes
Yes
Xtro\celf1
1 of 13
No
No
Xtro\celf2
1 of 13
No
No
Xtro\celf4
1 of 13
No
No
Xtro\celf5
1 of 13
No
No
Xtro\cirbp
1 of 13
No
No
Xtro\cpeb3
1 of 13
No
No
Xtro\cpeb4
1 of 13
No
No
Xtro\dazap1
1 of 13
No
No
Xtro\elavl1
1 of 13
No
No
Xtro\elavl2
1 of 13
No
No
Xtro\elavl3
1 of 13
No
No
Xtro\elavl4
1 of 13
No
No
Xtro\hnrnpa1
1 of 13
No
No
Xtro\hnrnpa3
1 of 13
No
No
Xtro\jpt2
1 of 13
No
No
Xtro\mrps9
1 of 13
No
No
Xtro\msi1
1 of 13
No
No
Xtro\msi2
1 of 13
No
No
Xtro\ncbp2
1 of 13
No
No
Xtro\nifk
1 of 13
No
No
Xtro\nono
1 of 13
No
No
Xtro\pabpc1l
1 of 13
No
No
Xtro\pabpn1
1 of 13
No
No
Xtro\rbfox2
1 of 13
No
No
Xtro\rbm12b.1
1 of 13
No
No
Xtro\rbm15b
1 of 13
No
No
Xtro\rbm19
1 of 13
No
No
Xtro\rbm24
1 of 13
No
No
Xtro\rbm34
1 of 13
No
No
Xtro\rbm38
1 of 13
No
No
Xtro\sf3b4
1 of 13
No
No
Xtro\sf3b6
1 of 13
No
No
Xtro\slirp
1 of 13
No
No
Xtro\snrpa
1 of 13
No
No
Xtro\srek1
1 of 13
No
No
Xtro\srsf1
1 of 13
No
No
Xtro\tardbp
1 of 13
No
No
Xtro\tia1
1 of 13
No
No
Xtro\tra2a
1 of 13
No
No
Xtro\tra2b
1 of 13
No
No
Xtro\tram2
1 of 13
No
No
Xtro\zcrb1
1 of 13
No
Yes
Danio rerio (Zebrafish) (68)
Drer\hnrnpd
10 of 14
Yes
Yes
Drer\hnrnpdl
10 of 14
Yes
Yes
Drer\hnrnpaba
9 of 14
No
Yes
Drer\hnrnpabb
9 of 14
No
Yes
Drer\dazap1
2 of 14
No
No
Drer\msi2a
2 of 14
No
No
Drer\msi2b
2 of 14
No
No
Drer\celf1
1 of 14
No
No
Drer\celf2
1 of 14
No
No
Drer\celf4
1 of 14
No
No
Drer\celf5a
1 of 14
No
No
Drer\celf6
1 of 14
No
No
Drer\cpeb1a
1 of 14
No
No
Drer\cpeb1b
1 of 14
No
No
Drer\cpeb2
1 of 14
No
No
Drer\cpeb3
1 of 14
No
No
Drer\cpeb4a
1 of 14
No
No
Drer\cpeb4b
1 of 14
No
No
Drer\dazl
1 of 14
No
No
Drer\elavl4
1 of 14
No
No
Drer\hnrnpa0a
1 of 14
No
No
Drer\hnrnpa0b
1 of 14
No
No
Drer\hnrnpa0l
1 of 14
No
No
Drer\hnrnpa1a
1 of 14
No
No
Drer\hnrnpa1b
1 of 14
No
No
Drer\hnrnpa3
1 of 14
No
No
Drer\LOC100537556
1 of 14
No
No
Drer\msi1a
1 of 14
No
No
Drer\msi1b
1 of 14
No
No
Drer\ncbp2
1 of 14
No
No
Drer\ncl
1 of 14
No
No
Drer\nono
1 of 14
No
No
Drer\pabpc1a
1 of 14
No
No
Drer\pabpc4
1 of 14
No
No
Drer\pabpn1
1 of 14
No
No
Drer\pabpn1l
1 of 14
No
No
Drer\ppie
1 of 14
No
No
Drer\pspc1
1 of 14
No
No
Drer\rbfox1l
1 of 14
No
No
Drer\rbfox3a
1 of 14
No
No
Drer\rbfox3b
1 of 14
No
No
Drer\rbm4.1
1 of 14
No
No
Drer\rbm4.2
1 of 14
No
No
Drer\rbm7
1 of 14
No
No
Drer\rbm24a
1 of 14
No
No
Drer\rbm24b
1 of 14
No
No
Drer\rbm34
1 of 14
No
No
Drer\rbm38
1 of 14
No
No
Drer\sart3
1 of 14
No
No
Drer\sf3b6
1 of 14
No
No
Drer\si:ch1073-335m2.2
1 of 14
No
No
Drer\slirp
1 of 14
No
No
Drer\snrnp35
1 of 14
No
Yes
Drer\snrpa
1 of 14
No
No
Drer\srek1
1 of 14
No
No
Drer\srsf1a
1 of 14
No
No
Drer\srsf1b
1 of 14
No
No
Drer\srsf9
1 of 14
No
No
Drer\srsf10b
1 of 14
No
Yes
Drer\syncrip
1 of 14
No
No
Drer\tardbpa
1 of 14
No
No
Drer\tardbpb
1 of 14
No
No
Drer\tia1
1 of 14
No
No
Drer\tia1l
1 of 14
No
No
Drer\tial1
1 of 14
No
No
Drer\tra2a
1 of 14
No
No
Drer\tra2b
1 of 14
No
No
Drer\zgc:165603
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (44)
Cele\sqd-1
7 of 14
Yes
Yes
Cele\msi-1
2 of 14
No
No
Cele\cpb-1
1 of 14
No
No
Cele\cpb-3
1 of 14
No
No
Cele\cpf-2
1 of 14
No
No
Cele\EEED8.4
1 of 14
No
No
Cele\EEED8.12
1 of 14
No
No
Cele\etr-1
1 of 14
No
No
Cele\exc-7
1 of 14
No
No
Cele\fog-1
1 of 14
No
No
Cele\grld-1
1 of 14
No
No
Cele\hrpa-1
1 of 14
No
No
Cele\hrpa-2
1 of 14
No
No
Cele\pab-1
1 of 14
No
No
Cele\pab-2
1 of 14
No
No
Cele\pabp-2
1 of 14
No
No
Cele\R05D3.8
1 of 14
No
Yes
Cele\R06C1.4
1 of 14
No
No
Cele\rbm-3.1
1 of 14
No
No
Cele\rbm-3.2
1 of 14
No
No
Cele\rbm-25
1 of 14
No
No
Cele\rbm-28
1 of 14
No
No
Cele\rbm-34
1 of 14
No
No
Cele\rbm-39
1 of 14
No
No
Cele\rbm-42
1 of 14
No
No
Cele\rbmx-2
1 of 14
No
No
Cele\rnp-7
1 of 14
No
No
Cele\rnp-9
1 of 14
No
No
Cele\rsp-4
1 of 14
No
No
Cele\rsp-6
1 of 14
No
No
Cele\rsp-8
1 of 14
No
No
Cele\sap-49
1 of 14
No
No
Cele\sart-3
1 of 14
No
No
Cele\sftb-6
1 of 14
No
No
Cele\sgnh-1
1 of 14
No
No
Cele\slrp-1
1 of 14
No
No
Cele\spn-4
1 of 14
No
No
Cele\sup-12
1 of 14
No
No
Cele\T08B6.1
1 of 14
No
No
Cele\tdp-1
1 of 14
No
No
Cele\tiar-1
1 of 14
No
No
Cele\tiar-2
1 of 14
No
No
Cele\unc-75
1 of 14
No
No
Cele\Y57G11A.5
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (56)
Agam\AgaP_AGAP006668
11 of 12
Yes
Yes
Agam\AgaP_AGAP000399
8 of 12
No
Yes
Agam\AgaP_AGAP001993
2 of 12
No
No
Agam\AgaP_AGAP000965
1 of 12
No
No
Agam\AgaP_AGAP000977
1 of 12
No
No
Agam\AgaP_AGAP001419
1 of 12
No
No
Agam\AgaP_AGAP001538
1 of 12
No
No
Agam\AgaP_AGAP001640
1 of 12
No
No
Agam\AgaP_AGAP001643
1 of 12
No
No
Agam\AgaP_AGAP001883
1 of 12
No
No
Agam\AgaP_AGAP001930
1 of 12
No
No
Agam\AgaP_AGAP002256
1 of 12
No
No
Agam\AgaP_AGAP002296
1 of 12
No
No
Agam\AgaP_AGAP002335
1 of 12
No
No
Agam\AgaP_AGAP002374
1 of 12
No
No
Agam\AgaP_AGAP002655
1 of 12
No
No
Agam\AgaP_AGAP002780
1 of 12
No
No
Agam\AgaP_AGAP002959
1 of 12
No
No
Agam\AgaP_AGAP003170
1 of 12
No
No
Agam\AgaP_AGAP003171
1 of 12
No
No
Agam\AgaP_AGAP003172
1 of 12
No
No
Agam\AgaP_AGAP003173
1 of 12
No
No
Agam\AgaP_AGAP003497
1 of 12
No
No
Agam\AgaP_AGAP003899
1 of 12
No
No
Agam\AgaP_AGAP004414
1 of 12
No
No
Agam\AgaP_AGAP004950
1 of 12
No
No
Agam\AgaP_AGAP005006
1 of 12
No
No
Agam\AgaP_AGAP005117
1 of 12
No
No
Agam\AgaP_AGAP005127
1 of 12
No
No
Agam\AgaP_AGAP005292
1 of 12
No
No
Agam\AgaP_AGAP005506
1 of 12
No
No
Agam\AgaP_AGAP006089
1 of 12
No
No
Agam\AgaP_AGAP006365
1 of 12
No
No
Agam\AgaP_AGAP006656
1 of 12
No
No
Agam\AgaP_AGAP006755
1 of 12
No
No
Agam\AgaP_AGAP006798
1 of 12
No
No
Agam\AgaP_AGAP007325
1 of 12
No
No
Agam\AgaP_AGAP008433
1 of 12
No
No
Agam\AgaP_AGAP009179
1 of 12
No
No
Agam\AgaP_AGAP009474
1 of 12
No
No
Agam\AgaP_AGAP009477
1 of 12
No
No
Agam\AgaP_AGAP009742
1 of 12
No
No
Agam\AgaP_AGAP009810
1 of 12
No
No
Agam\AgaP_AGAP009952
1 of 12
No
No
Agam\AgaP_AGAP009990
1 of 12
No
No
Agam\AgaP_AGAP010553
1 of 12
No
No
Agam\AgaP_AGAP010918
1 of 12
No
No
Agam\AgaP_AGAP011092
1 of 12
No
No
Agam\AgaP_AGAP011637
1 of 12
No
No
Agam\AgaP_AGAP011884
1 of 12
No
No
Agam\AgaP_AGAP011956
1 of 12
No
No
Agam\AgaP_AGAP013048
1 of 12
No
No
Agam\AgaP_AGAP013051
1 of 12
No
No
Agam\AgaP_AGAP013420
1 of 12
No
Yes
Agam\AgaP_AGAP013440
1 of 12
No
No
Agam\NCBP2_ANOGA
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (134)
Atha\AT2G33410
3 of 13
Yes
No
Atha\AT3G07810
3 of 13
Yes
No
Atha\AT3G13224
3 of 13
Yes
No
Atha\AT4G14300
3 of 13
Yes
No
Atha\AT4G26650
3 of 13
Yes
No
Atha\AT1G17640
2 of 13
No
No
Atha\AT5G08695
2 of 13
No
No
Atha\AT5G40490
2 of 13
No
No
Atha\AT5G47620
2 of 13
No
No
Atha\AT5G55550
2 of 13
No
No
Atha\AT1G01080
1 of 13
No
No
Atha\AT1G03457
1 of 13
No
No
Atha\AT1G06960
1 of 13
No
No
Atha\AT1G20880
1 of 13
No
No
Atha\AT1G22330
1 of 13
No
No
Atha\AT1G22910
1 of 13
No
No
Atha\AT1G33470
1 of 13
No
No
Atha\AT1G60000
1 of 13
No
No
Atha\AT1G60900
1 of 13
No
No
Atha\AT1G76460
1 of 13
No
No
Atha\AT1G78260
1 of 13
No
No
Atha\AT2G14870
1 of 13
No
No
Atha\AT2G16940
1 of 13
No
No
Atha\AT2G19380
1 of 13
No
No
Atha\AT2G21440
1 of 13
No
No
Atha\AT2G21690
1 of 13
No
No
Atha\AT2G22100
1 of 13
No
No
Atha\AT2G24350
1 of 13
No
Yes
Atha\AT2G27330
1 of 13
No
Yes
Atha\AT2G35410
1 of 13
No
No
Atha\AT2G37220
1 of 13
No
No
Atha\AT2G41060
1 of 13
No
No
Atha\AT2G46780
1 of 13
No
No
Atha\AT2G47310
1 of 13
No
No
Atha\AT3G06970
1 of 13
No
No
Atha\AT3G08000
1 of 13
No
No
Atha\AT3G12640
1 of 13
No
No
Atha\AT3G14100
1 of 13
No
No
Atha\AT3G15010
1 of 13
No
No
Atha\AT3G20930
1 of 13
No
Yes
Atha\AT3G46020
1 of 13
No
Yes
Atha\AT3G52660
1 of 13
No
No
Atha\AT4G13860
1 of 13
No
Yes
Atha\AT4G19610
1 of 13
No
No
Atha\AT4G35785
1 of 13
No
No
Atha\AT4G36960
1 of 13
No
No
Atha\AT5G04600
1 of 13
No
No
Atha\AT5G06210
1 of 13
No
Yes
Atha\AT5G09880
1 of 13
No
No
Atha\AT5G10350
1 of 13
No
No
Atha\AT5G11412
1 of 13
No
No
Atha\AT5G12190
1 of 13
No
No
Atha\AT5G19030
1 of 13
No
Yes
Atha\AT5G19350
1 of 13
No
No
Atha\AT5G19960
1 of 13
No
Yes
Atha\AT5G46840
1 of 13
No
No
Atha\AT5G53680
1 of 13
No
No
Atha\AT5G53720
1 of 13
No
No
Atha\AT5G54580
1 of 13
No
Yes
Atha\AT5G59860
1 of 13
No
Yes
Atha\AT5G59865
1 of 13
No
No
Atha\AT5G65260
1 of 13
No
No
Atha\ATRBP45C
1 of 13
No
No
Atha\ATRZ-1A
1 of 13
No
No
Atha\AtRZ-1b
1 of 13
No
No
Atha\AtRZ-1c
1 of 13
No
Yes
Atha\ATU2AF65A
1 of 13
No
No
Atha\CBP20
1 of 13
No
No
Atha\CCR1
1 of 13
No
No
Atha\CID8
1 of 13
No
No
Atha\CID9
1 of 13
No
No
Atha\CID10
1 of 13
No
No
Atha\CID11
1 of 13
No
No
Atha\CID12
1 of 13
No
Yes
Atha\CID13
1 of 13
No
No
Atha\CP29
1 of 13
No
No
Atha\CP31B
1 of 13
No
No
Atha\CP33
1 of 13
No
No
Atha\CYP59
1 of 13
No
No
Atha\EMB140
1 of 13
No
No
Atha\emb2444
1 of 13
No
No
Atha\FCA
1 of 13
No
No
Atha\FPA
1 of 13
No
No
Atha\GRP4
1 of 13
No
No
Atha\GRP7
1 of 13
No
No
Atha\GR-RBP1
1 of 13
No
No
Atha\GR-RBP2
1 of 13
No
No
Atha\GR-RBP3
1 of 13
No
Yes
Atha\GR-RBP5
1 of 13
No
Yes
Atha\GR-RBP6
1 of 13
No
No
Atha\LIF2
1 of 13
No
No
Atha\ML2
1 of 13
No
No
Atha\ML4
1 of 13
No
Yes
Atha\NUC-L1
1 of 13
No
No
Atha\NUC-L2
1 of 13
No
No
Atha\PAB1
1 of 13
No
No
Atha\PAB2
1 of 13
No
No
Atha\PAB3
1 of 13
No
No
Atha\PAB4
1 of 13
No
No
Atha\PAB5
1 of 13
No
No
Atha\PAB6
1 of 13
No
No
Atha\PAB7
1 of 13
No
No
Atha\PAB8
1 of 13
No
No
Atha\PABN1
1 of 13
No
No
Atha\PHIP1
1 of 13
No
No
Atha\PSRP2
1 of 13
No
No
Atha\PTB1
1 of 13
No
No
Atha\RBP1
1 of 13
No
No
Atha\RBP31
1 of 13
No
No
Atha\RBP45A
1 of 13
No
No
Atha\RBP45B
1 of 13
No
No
Atha\RBP47A
1 of 13
No
No
Atha\RBP47B
1 of 13
No
No
Atha\RBP47C'
1 of 13
No
No
Atha\RBP47C
1 of 13
No
No
Atha\RBP-DR1
1 of 13
No
No
Atha\RPS19
1 of 13
No
No
Atha\SC35
1 of 13
No
No
Atha\SCL30A
1 of 13
No
No
Atha\SR30
1 of 13
No
No
Atha\SR34
1 of 13
No
No
Atha\SR34b
1 of 13
No
No
Atha\SR45a
1 of 13
No
No
Atha\SR45
1 of 13
No
No
Atha\SUA
1 of 13
No
No
Atha\U1-70K
1 of 13
No
No
Atha\U1A
1 of 13
No
No
Atha\U2B''
1 of 13
No
No
Atha\U11/U12-31K
1 of 13
No
Yes
Atha\UBA1A
1 of 13
No
No
Atha\UBA2A
1 of 13
No
No
Atha\UBP1A
1 of 13
No
No
Atha\UBP1B
1 of 13
No
No
Atha\Y14
1 of 13
No
No
Saccharomyces cerevisiae (Brewer's yeast) (15)
Scer\HRP1
4 of 13
Yes
No
Scer\GBP2
1 of 13
No
No
Scer\IST3
1 of 13
No
No
Scer\MRD1
1 of 13
No
No
Scer\NAM8
1 of 13
No
No
Scer\NOP6
1 of 13
No
Yes
Scer\NOP12
1 of 13
No
No
Scer\NOP13
1 of 13
No
Yes
Scer\NPL3
1 of 13
No
No
Scer\NSR1
1 of 13
No
Yes
Scer\PAB1
1 of 13
No
No
Scer\PUB1
1 of 13
No
No
Scer\RNA15
1 of 13
No
No
Scer\SGN1
1 of 13
No
No
Scer\SNP1
1 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (11)
Spom\SPBC660.15
3 of 12
Yes
No
Spom\gar2
2 of 12
No
Yes
Spom\ctf1
1 of 12
No
No
Spom\nop12
1 of 12
No
No
Spom\pab2
1 of 12
No
No
Spom\rnp24
1 of 12
No
Yes
Spom\sab14
1 of 12
No
No
Spom\SPAC25G10.01
1 of 12
No
No
Spom\SPBC13A2.01c
1 of 12
No
No
Spom\SPBC365.04c
1 of 12
No
No
Spom\usp101
1 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:sqd. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (57)
msi
4 of 13
Rbp6
4 of 13
Hrb27C
3 of 13
Hrb87F
3 of 13
Hrb98DE
3 of 13
Caper
2 of 13
CG34354
2 of 13
cocoon
2 of 13
Rb97D
2 of 13
Rbp4
2 of 13
SLIRP1
2 of 13
SLIRP2
2 of 13
Syp
2 of 13
TBPH
2 of 13
bol
1 of 13
bru1
1 of 13
bru2
1 of 13
bru3
1 of 13
Cbp20
1 of 13
CG2931
1 of 13
CG3335
1 of 13
CG3594
1 of 13
CG4612
1 of 13
CG6937
1 of 13
CG10466
1 of 13
CG11454
1 of 13
CG12288
1 of 13
CG34334
1 of 13
CstF64
1 of 13
elav
1 of 13
fne
1 of 13
hfp
1 of 13
lark
1 of 13
LS2
1 of 13
maca
1 of 13
mod
1 of 13
nito
1 of 13
orb2
1 of 13
orb
1 of 13
Pabp2
1 of 13
Ppil4
1 of 13
Rbp1-like
1 of 13
Rbp1
1 of 13
Rbp9
1 of 13
Ref1
1 of 13
rin
1 of 13
Rnp4F
1 of 13
SC35
1 of 13
Secp43
1 of 13
Sf3b6
1 of 13
snf
1 of 13
Spx
1 of 13
ssx
1 of 13
Sxl
1 of 13
tra2
1 of 13
trv
1 of 13
tsu
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 1 )
Modifiers Based on Experimental Evidence ( 1 )
Allele
Disease
Interaction
References
sqdGD8593
exacerbates  neurodegenerative disease
modeled by TBPHΔ23, TBPHRNAi.UAS.cUa
(Appocher et al., 2017)
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
HNRNPD; heterogeneous nuclear ribonucleoprotein D
11 of 14
601324
      HNRNPAB; heterogeneous nuclear ribonucleoprotein A/B
      9 of 14
      602688
          HNRNPDL; heterogeneous nuclear ribonucleoprotein D like
          9 of 14
          HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE PROTEIN; HNRNPDL
           
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          Interaction Browsers
          View in FlyBase Interactions Browser   View in MIST tool (external link)
          Please see the Physical Interaction reports below for full details
          RNA-protein
          Physical Interaction
          Assay
          References
          sqd - Dscam1
          anti bait coimmunoprecipitation, nucleotide sequence identification
          (Olson et al., 2007)
          sqd - Imp
          anti bait coimmunoprecipitation, peptide massfingerprinting, electrophoretic mobility shift assay, autoradiography, western blot
          (Hansen et al., 2015, Clouse et al., 2008, Geng and Macdonald, 2006)
          sqd - Mi-2
          iclip, partial RNA sequence identification, anti tag coimmunoprecipitation, quantitative reverse transcription pcr
          (Ullah et al., 2022)
          sqd - Unr
          anti bait coimmunoprecipitation, quantitative reverse transcription pcr
          (Mihailovich et al., 2012)
          sqd - bcd
          anti tag coimmunoprecipitation, primer specific pcr
          (McDermott and Davis, 2013, McDermott et al., 2012)
          sqd - grk
          anti bait coimmunoprecipitation, nucleic acid uv cross-linking assay, autoradiography, anti tag coimmunoprecipitation, primer specific pcr, phage display, pull down, peptide massfingerprinting, quantitative reverse transcription pcr
          (Li et al., 2014, McDermott and Davis, 2013, McDermott et al., 2012, Rom et al., 2007, Norvell et al., 2005, Norvell et al., 1999)
          sqd - lncRNA:Hsrω
          pull down, anti tag western blot, anti bait coimmunoprecipitation, primer specific pcr, southern blot
          (Onorati et al., 2011, Prasanth et al., 2000)
          sqd - osk
          anti tag coimmunoprecipitation, primer specific pcr, anti bait coimmunoprecipitation, nucleic acid uv cross-linking assay, autoradiography
          (McDermott and Davis, 2013, McDermott et al., 2012, Norvell et al., 2005)
          sqd - shep
          coimmunoprecipitation, quantitative reverse transcription pcr
          (Olesnicky et al., 2018)
          protein-protein
          Physical Interaction
          Assay
          References
          sqd - Akt
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - Art1
          methyltransferase assay, autoradiography
          (Boulanger et al., 2004)
          sqd - Dsor1
          anti tag coimmunoprecipitation, peptide massfingerprinting
          (Friedman et al., 2011)
          sqd - Egfr
          anti tag coimmunoprecipitation, peptide massfingerprinting
          (Friedman et al., 2011)
          sqd - Hrb27C
          two hybrid, anti bait coimmunoprecipitation, molecular weight estimation by staining, molecular weight estimation by autoradiography, peptide massfingerprinting, western blot
          (Clouse et al., 2008, Goodrich et al., 2004, Amero et al., 1993, Matunis et al., 1992)
          sqd - Hrb87F
          anti bait coimmunoprecipitation, western blot, molecular weight estimation by autoradiography, molecular weight estimation by staining
          (Prasanth et al., 2000, Amero et al., 1993, Matunis et al., 1992)
          sqd - Hrb98DE
          anti bait coimmunoprecipitation, molecular weight estimation by autoradiography, molecular weight estimation by staining
          (Amero et al., 1993, Matunis et al., 1992)
          sqd - Hrp39
          anti bait coimmunoprecipitation, molecular weight estimation by staining
          (Amero et al., 1993)
          sqd - Hrp44
          anti bait coimmunoprecipitation, molecular weight estimation by staining
          (Amero et al., 1993)
          sqd - Hrp62
          anti bait coimmunoprecipitation, molecular weight estimation by staining
          (Amero et al., 1993)
          sqd - Hrp70
          anti bait coimmunoprecipitation, molecular weight estimation by staining
          (Amero et al., 1993)
          sqd - Hrp75
          anti bait coimmunoprecipitation, molecular weight estimation by staining
          (Amero et al., 1993)
          sqd - Imp
          anti bait coimmunoprecipitation, peptide massfingerprinting, electrophoretic mobility shift assay, autoradiography, western blot
          (Hansen et al., 2015, Clouse et al., 2008, Geng and Macdonald, 2006)
          sqd - Mettl14
          anti tag coimmunoprecipitation, anti tag western blot
          (Tang et al., 2021)
          sqd - Mkrn1
          anti tag coimmunoprecipitation, Identification by mass spectrometry, anti tag western blot
          (Dold et al., 2020)
          sqd - Parp1
          anti tag coimmunoprecipitation, western blot
          (Ji and Tulin, 2009)
          sqd - Pdk1
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - Pep
          anti bait coimmunoprecipitation, western blot
          (Amero et al., 1993)
          sqd - Pi3K21B
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - RasGAP1
          anti tag coimmunoprecipitation, peptide massfingerprinting
          (Friedman et al., 2011)
          sqd - Rbf
          anti tag coimmunoprecipitation, western blot, multidimensional protein identification technology, anti bait coimmunoprecipitation
          (Ahlander and Bosco, 2009)
          sqd - Rheb
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - S6k
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - S6kII
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - Sumo
          pull down, covalent binding, western blot, anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Nie et al., 2009)
          sqd - Syp
          anti bait coimmunoprecipitation, western blot
          (McDermott et al., 2012)
          sqd - TBPH
          anti bait coimmunoprecipitation, western blot, far western blotting, Identification by mass spectrometry
          (Lo Piccolo et al., 2018, Romano et al., 2014)
          sqd - Thor
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - Tnpo
          pull down, autoradiography
          (Norvell et al., 1999)
          sqd - Tsc1
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - bru1
          pull down, autoradiography, anti bait coimmunoprecipitation, western blot
          (Norvell et al., 1999)
          sqd - cnk
          anti tag coimmunoprecipitation, peptide massfingerprinting
          (Friedman et al., 2011)
          sqd - cup
          anti bait coimmunoprecipitation, western blot, peptide massfingerprinting, anti tag coimmunoprecipitation
          (Clouse et al., 2008)
          sqd - fl(2)d
          anti tag coimmunoprecipitation, anti tag western blot
          (Tang et al., 2021)
          sqd - foxo
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - fs(1)K10
          pull down, autoradiography
          (Norvell et al., 1999)
          sqd - gig
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          sqd - nito
          anti tag coimmunoprecipitation, anti tag western blot
          (Tang et al., 2021)
          sqd - orb2
          anti tag coimmunoprecipitation, western blot
          (Khan et al., 2015, Majumdar et al., 2012)
          sqd - pAbp
          anti tag coimmunoprecipitation, western blot, anti bait coimmunoprecipitation, peptide massfingerprinting
          (Clouse et al., 2008)
          sqd - rictor
          anti tag coimmunoprecipitation, Identification by mass spectrometry
          (Vinayagam et al., 2016)
          Summary of Genetic Interactions
          Interaction Browsers
          View in FlyBase Interactions Browser   View in MIST tool (external link)
          Please look at the allele data for full details of the genetic interactions
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          sqd
          enhanceable
          Hrb27C
          (Goodrich et al., 2004)
          sqd
          suppressible
          otu
          (Goodrich et al., 2004)
          sqd
          enhanceable
          Rbf
          (Ahlander and Bosco, 2009)
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Imp
          enhanceable
          sqd
          (Geng and MacDonald, 2007)
          Rbf
          enhanceable
          sqd
          (Ahlander and Bosco, 2009)
          Rpp30
          suppressible
          sqd
          (Molla-Herman et al., 2015)
          TBPH
          enhanceable
          sqd
          (Appocher et al., 2017)
          External Data
          Subunit Structure (UniProtKB)
          Interacts with bru1/Bruno; the interaction is direct but weak, and may play a role in regulation of grk mRNA localization and translation.
          (UniProt, Q08473 )
          Linkouts
          DroID - A comprehensive database of gene and protein interactions.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          FlyBase
          External Links
          External Data
          Linkouts
          KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
          Class of Gene
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          3R
          Recombination map
          3-54
          Cytogenetic map
          87F5-87F6
          Sequence location
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          87F5-87F6
          Limits computationally determined from genome sequence between P{PZ}CtBP03463 and P{lacW}B52s2249&P{lacW}flflL4179
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          87F2-87F3
          (determined by in situ hybridisation) 87F3--4 (determined by in situ hybridisation)
          (Spradling et al., 1999)
          87F3-87F4
          (determined by in situ hybridisation) 87F2--3 (determined by in situ hybridisation)
          (Perrimon et al., 1996)
          87F3-87F4
          (BDGP Project Members, 1994-1999)
          87F-87F
          (determined by in situ hybridisation)
          (Kelley, 1993, Matunis et al., 1992)
          87F4-87F10
          (determined by in situ hybridisation)
          (Kelley, 1992)
          Experimentally Determined Recombination Data
          Location

          3-54

          (FlyBase, 2016)

          3-51.0

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (18)
          Genomic Clones (18)
           

          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

          cDNA Clones (819)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          Antibody Information
          Laboratory Generated Antibodies
           

          polyclonal

          (Blanchette et al., 2009)

          monoclonal

          (Goodrich et al., 2004, Matunis et al., 1992)
          Commercially Available Antibodies
           
          Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
          Cell Line Information
          Publicly Available Cell Lines
           
            Other Stable Cell Lines
             
              Other Comments

              Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene.

              (Hansen et al., 2009)

              Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells.

              (Nybakken et al., 2005)

              New annotation (CR33328) in release 3.2 of the genome annotation.

              (FlyBase Genome Annotators, 2004)

              ftz transcript localization in blastoderm embryos involves sqd, which selectively binds to the ftz 3' UTR.

              (Lall et al., 1999)

              Sxl does not form an immunoprecipitable complex with sqd.

              (Deshpande et al., 1996)

              The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation. sqd is required for germ cell viability or early oogenesis.

              (Perrimon et al., 1996)

              sqd expression patterns in wild type and mutant ovaries demonstrates an essential role of sqd gene product in the germ line during oogenesis.

              (Matunis et al., 1994)

              Phenotypic and molecular characterisation of sqd demonstrates that the RNA-binding gene product plays a central role in establishing egg polarity.

              (Kelley, 1993)

              A sequence comparison and numerical analysis of the RRM-containing (RNA recognition motif) proteins suggests that functionally related RRM-containing proteins have significant sequence similarities in their RRMs.

              (Kim and Baker, 1993)

              The distribution of the hnRNP protein sqd on nascent transcripts from polytene chromosomes has been studied.

              (Matunis et al., 1993)

              A sqd cDNA clone has been isolated and sequenced.

              (Matunis et al., 1992)
              Relationship to Other Genes
              Source for database merge of

              Source for merge of: CR33328 BcDNA:GM03761

              (Rana, 2004.7.2)

              Source for merge of: sqd l(3)j4B4

              (FlyBase, 1996-)

              Source for merge of: sqd Rbp3

              (Misra, 2000.7.28)

              Source for merge of: CG16901 CG17791

              (FlyBase Genome Annotators, 2002-2003)

              Source for merge of: sqd CR33328

              (FlyBase Genome Annotators, 2011)
              Additional comments

              Annotation CG16901 merged with annotation CR33328 in release 5.40 of the genome annotation; CR33328 corresponds to 3' UTR of CG16901.

              (FlyBase Genome Annotators, 2011)

              Annotations CG16901 and CG17791 merged as sqd in release 3 of the genome annotation.

              (FlyBase Genome Annotators, 2002-2003)
              Nomenclature History
              Source for database identify of

              Source for identity of: sqd CG17791

              (Gabrielian, 1999.11)
              Nomenclature comments
              Etymology
              Synonyms and Secondary IDs (27)
              Reported As
              Symbol Synonym
              BcDNA:GM03761
              CG16901
              (Appocher et al., 2017, Kolkhof et al., 2017, Meadows, 2017.9.14, Aradska et al., 2015, Brooks et al., 2015, Horan et al., 2015, Hosono et al., 2015, Rosa-Ferreira et al., 2015, Cammarato et al., 2011, Ni et al., 2011.7.19, Ellis and Carney, 2010, Ni et al., 2010.12.1, Blagden et al., 2009, Hansen et al., 2009, Herold et al., 2009, Ni et al., 2008, Puri et al., 2008, Quinones-Coello, 2007, McIntyre et al., 2006, Nybakken et al., 2005, Oliver, 2001.8.16)
              CG17791
              (Labourier et al., 2002)
              CR33328
              HRP40
              (Nakamura et al., 1994)
              Hrb87
              (Kim and Baker, 1993)
              Hrb87Fb
              Hrp40
              (Ustaoglu et al., 2019, Jansen and Niessing, 2012, Kuan et al., 2009, Jolly and Lakhotia, 2006, Lakhotia, 2003, Rajendra et al., 2001, Hovemann et al., 2000, Prasanth et al., 2000)
              RRM3
              (Kim, 1993.3.10)
              Rbp3
              SQD
              (Rom et al., 2007, Sofola et al., 2007)
              Sqd
              (Wilby and Weil, 2023, Dold et al., 2020, Appocher et al., 2017, McDermott and Davis, 2013, O'Sullivan et al., 2013, McDermott et al., 2012, Vazquez-Pianzola and Suter, 2012, Onorati et al., 2011, Shimada et al., 2011, Ji and Tulin, 2009, Norvell et al., 2008, Puri et al., 2008, Meigh et al., 2007, Rasmussen and Kellis, 2007, Minakhina and Steward, 2005)
              Squid
              (Layalle et al., 2021, Lo Piccolo et al., 2018, Jansen and Niessing, 2012, Izaurralde, 1999)
              fs(3)00048
              hnRNP 1
              (Kiebler and DesGroseillers, 2000)
              hnRNP A
              (Jolly and Lakhotia, 2006, Lakhotia, 2003)
              hrp40
              (Horan et al., 2015, Hartmann et al., 2011, Blanchette et al., 2009, Olson et al., 2007, Lakhotia et al., 1999, Reim et al., 1999, Deshpande et al., 1996, Matunis et al., 1994, Samuels et al., 1994, Amero et al., 1993, Matunis et al., 1993, Weeks et al., 1993, Matunis et al., 1992, Matunis et al., 1992)
              l(3)EP3631
              (Francis-Lang, 1999.8.10)
              l(3)j4B4
              (Spradling et al., 1999, Perrimon et al., 1996, BDGP Project Members, 1994-1999)
              l(3)j6E3
              l(3)j8E7
              rrm3
              (Kim and Baker, 1993)
              sqd
              (Finger et al., 2023, Heigwer et al., 2023, Riemondy et al., 2023, Titlow et al., 2023, Ullah et al., 2022, Hall et al., 2021, Kim et al., 2021, Lindsey et al., 2021, Ramesh et al., 2020, Samuels et al., 2020, Sapiro et al., 2020, Fingerhut et al., 2019, Park et al., 2019, Bonneaud et al., 2017, Transgenic RNAi Project members, 2017-, Clandinin and Owens, 2016-, Davidson et al., 2016, Lee et al., 2016, Lefebvre et al., 2016, Mao et al., 2016, Brooks et al., 2015, Dent et al., 2015, Fear et al., 2015, Hansen et al., 2015, Horan et al., 2015, Khan et al., 2015, Ashwal-Fluss et al., 2014, Li et al., 2014, Olesnicky et al., 2014, Baumgartner et al., 2013, Kwon et al., 2013, Mihailovich et al., 2012, Baxley et al., 2011, FlyBase Genome Annotators, 2011, Friedman et al., 2011, Serbus et al., 2011, Arancio et al., 2010, Ellis and Carney, 2010, Klusza and Deng, 2010, Ahlander and Bosco, 2009, Dworkin et al., 2009, Hansen et al., 2009, Herold et al., 2009, Kalifa et al., 2009, Telonis-Scott et al., 2009, Clouse et al., 2008, Jaramillo et al., 2008, Jaramillo et al., 2008, Akdemir et al., 2007, Buszczak et al., 2007, Delanoue et al., 2007, Geng and MacDonald, 2007, Quinones-Coello, 2007, Sofola et al., 2007, Geng and Macdonald, 2006, McIntyre et al., 2006, Norvell et al., 2005, Nybakken et al., 2005, Gim et al., 2001)
              squid
              (Cáceres and Nilson, 2009)
              Name Synonyms
              RNA-binding protein 3
              Squid
              (Bayer et al., 2024, Lacroix et al., 2021, Sankaranarayanan and Weil, 2020, Li et al., 2014, Lowe et al., 2014, Romano et al., 2014, Jokhi et al., 2013, Majumdar et al., 2012, Serbus et al., 2011, Ahlander and Bosco, 2009, Ji and Tulin, 2009, Kalifa et al., 2009, Nie et al., 2009, Boylan et al., 2008, Clouse et al., 2008, Norvell et al., 2008, Meigh et al., 2007, Nurminsky, 2007, Vanzo et al., 2007, Geng and Macdonald, 2006, Jolly and Lakhotia, 2006, Manh et al., 2005, Van De Bor et al., 2005, Lakhotia, 2003, Gim et al., 2001)
              heterogeneous-nuclear-ribonucleoprotein-87Fb
              lethal (3) j4B4
              squid
              (Dyson et al., 2025, Schüpbach, 2019, Cammarato et al., 2011, Hartmann et al., 2011, Klusza and Deng, 2010, Kalifa et al., 2009, Chen and Schupbach, 2006)
              Secondary FlyBase IDs
              • FBgn0053328
              • FBgn0047283
              • FBgn0086897
              • FBgn0003498
              • FBgn0010257
              • FBgn0010299
              • FBgn0011398
              • FBgn0011413
              • FBgn0027643
              • FBgn0040556
              • FBgn0011363
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              Study result (0)
              Result
              Result Type
              Title
              External Crossreferences and Linkouts ( 96 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
              UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL - MARRVEL (model organism gene)
              Linkouts
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DroID - A comprehensive database of gene and protein interactions.
              Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
              KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              References (280)