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Citation
Tekotte, H., Davis, I. (2002). Intracellular mRNA localization: motors move messages.  Trends Genet. 18(12): 636--642.
FlyBase ID
FBrf0156097
Publication Type
Review
Abstract

Intracellular mRNA localization is a common mechanism of post-transcriptional regulation of gene expression. In a wide range of organisms, mRNA localization coupled with translational regulation target the proteins to their site of function. Here, we describe recent exciting evidence that some mRNAs are transported as particles along the cytoskeleton by the molecular motors dynein, kinesin or myosin. We discuss the key questions of how localized mRNAs might be linked to motors and what determines their cytoplasmic destinations.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Trends Genet.
    Title
    Trends in Genetics
    Publication Year
    1985-
    ISBN/ISSN
    0168-9525
    Data From Reference