wkl
Please see the JBrowse view of Dmel\btz for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Stop-codon suppression (UGA) postulated; FBrf0216884.
Gene model reviewed during 5.44
Gene model reviewed during 5.49
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\btz using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
btz protein is first expressed in germarium region 2, then accumulates in oocytes in germarium region 2b. At oogenesis stage S4, btz is localized to the posterior of the oocyte, then begins to lose posterior enrichment at oogenesis stage S6. By oogenesis stage 8, btz protein has dispersed throughout the cytoplasm of the oocyte. At oogenesis stage S9, btz is again enriched at the posterior of the oocyte, then begins to disperse into the cytoplasm at the beginning of oogenesis stage S10; by oogenesis stage S10b btz is completely dispersed. From oogenesis stage S4, btz protein is also concentrated in a punctate pattern around the nuclei of nurse cells, with a similar distribution in follicle cells beginning at oogenesis stage S6; this pattern is suggestive of an association with the nuclear pores of these cells. btz protein colocalizes with mago in a dense cloud around the ring canals, and at the posterior pole of stage 9 oocytes.
JBrowse - Visual display of RNA-Seq signals
View Dmel\btz in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for merge of: btz CG12878
Source for identity of: btz wkl
Based on the phenotype where osk mRNA becomes trapped at the anterior and fails to reach the posterior pole, the gene is named after Willem Barentsz, a seventeenth century explorer whose boat became frozen in the ice off Novaya Zemlya during an attempt to find a passage past the North pole.
