FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
sqd, pAbp
FlyBase ID
FBig0000102327
Interaction Network
Interactions Browser links
sqd network
pAbp network
Reported Interactions
FBrf0203066-11.coIP.WB
Reference
Clouse et al., 2008
Description
physical association
Assay
Collection
Source/Stage
ovary / adult stagefemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sqd 

Sqd

bait

HA tag

pAbp 

PABP55B

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female ovaries of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Clouse et al., 2008)

pAbp interacts with both HA-tagged sqd isoforms tested (SqdA and SqdS).

(Clouse et al., 2008)
FBrf0203066-2.coIP.MS
Reference
Clouse et al., 2008
Description
physical association
Assay
Collection
Source/Stage
ovary / adult stagefemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sqd 

Sqd

bait
pAbp 

PAPBP55B

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female ovaries of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Clouse et al., 2008)

Copurified proteins were identified only in sqd immunoprecipitation, and not in the negative control (dl immunoprecipitation).

(Clouse et al., 2008)
FBrf0203066-5.coIP.WB
Reference
Clouse et al., 2008
Description
physical association
Assay
Collection
Source/Stage
ovary / adult stagefemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sqd 

Sqd

bait
pAbp 

PABP55B

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female ovaries of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Clouse et al., 2008)

The sqd-pAbp interaction is RNA-dependent (disrupted by RNase A).

(Clouse et al., 2008)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)