FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
bru1, gcl
FlyBase ID
FBig0000097630
Interaction Network
Interactions Browser links
bru1 network
gcl network
Reported Interactions
FBrf0215430-2.PD.A
Reference
Moore et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
bru1 

Bru

bait

GST tag

bru1 
gcl 

gcl

prey

[35]S label

gcl 
gcl 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
gcl 
3-prime UTR A1 region
sufficient binding region
nt 1-130
gcl 
3-prime UTR A1 region
necessary binding region
nt 1-130
bru1 
C-terminal region
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro transcription.

(Moore et al., 2009)

Binding of aret protein to gcl RNA is mediated by the A1 region and does not require the BRE-like (BRL) region.

(Moore et al., 2009)

aret can bind the BRL motif in the gcl 3\' UTR if and only if it is present in multiple tandem copies.

(Moore et al., 2009)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)