FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
cos, Pp4-19C
FlyBase ID
FBig0000097644
Interaction Network
Interactions Browser links
cos network
Pp4-19C network
Reported Interactions
FBrf0206597-3.coIP.WB
Reference
Jia et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
cos 

Cos2

bait

HA tag

cos 
cos 
Pp4-19C 

PP4

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
cos 
microtubule binding domain
sufficient binding region
aa 1-389
cos 
cargo domain
sufficient binding region
aa 991-1201
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Jia et al., 2009)
FBrf0206597-5.PD.WB
Reference
Jia et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Pp4-19C 

PP4

bait

GST tag

cos 

Cos2

prey

His tag

cos 
cos 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
cos 
microtubule binding domain
sufficient binding region
aa 1-389
cos 
cargo domain
sufficient binding region
aa 991-1201
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Jia et al., 2009)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)