FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
E(spl)mδ-HLH, CtBP
FlyBase ID
FBig0000098278
Interaction Network
Interactions Browser links
E(spl)mδ-HLH network
CtBP network
Reported Interactions
FBrf0102176-3.Y2H
Reference
Poortinga et al., 1998
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
E(spl)mδ-HLH 

mδ/C

bait

fused to LexA DNA-binding domain

CtBP 

CtBP

prey

fused to VP16 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Poortinga et al., 1998)

CtBP binds h and @E(spl)mδ, but not other Hairy-class bHLH proteins.

(Poortinga et al., 1998)

Two-hybrid system: yeast LexA-BD/VP16-AD

(Poortinga et al., 1998)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)