FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Appl, Fas2
FlyBase ID
FBig0000098721
Interaction Network
Interactions Browser links
Appl network
Fas2 network
Reported Interactions
FBrf0187897-1.coIP.WB
Reference
Ashley et al., 2005
Description
physical association
Assay
Collection
Source/Stage
larval somatic muscle cell / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Appl 

APPL

bait
Fas2 

FasII

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Fas2, but not spectrin (which is also enriched at synaptic boutons), coimmunoprecipitates with Appl.

(Ashley et al., 2005)

Source was larval body wall muscle of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Ashley et al., 2005)
FBrf0187897-6.coIP.WB
Reference
Ashley et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Appl 

APPL

bait
Fas2 

FasII

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Fas2 coimmunoprecipitates with Appl in the presence or absence of X11L.

(Ashley et al., 2005)

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from transfected construct.

(Ashley et al., 2005)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)