FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
numb, aPKC
FlyBase ID
FBig0000099063
Interaction Network
Interactions Browser links
numb network
aPKC network
Reported Interactions
FBrf0206088-12.PD.WB
Reference
Wirtz-Peitz et al., 2008
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
numb 

Numb

bait

GST tag

numb 
aPKC 

aPKC

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
numb 
region
mutation disrupting interaction
aa 52

S52F

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type embryo extract.

(Wirtz-Peitz et al., 2008)

numb pulls down baz, par-6, AP-2α and aPKC, but not l(2)gl.

(Wirtz-Peitz et al., 2008)
FBrf0206088-15.PD.WB
Reference
Wirtz-Peitz et al., 2008
Description
physical association
Assay
Collection
Source/Stage
larval brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
numb 

Numb

bait

GST tag

numb 
aPKC 

aPKC

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
numb 
region
mutation disrupting interaction
aa 52

S52F

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type larval brain extract.

(Wirtz-Peitz et al., 2008)

numb pulls down baz, par-6, AP-2α and aPKC, but not l(2)gl.

(Wirtz-Peitz et al., 2008)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)