FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
DCTN2-p50, Lis-1
FlyBase ID
FBig0000099164
Interaction Network
Interactions Browser links
DCTN2-p50 network
Lis-1 network
Reported Interactions
FBrf0222317-45.PD.WB
Reference
Dix et al., 2013
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
DCTN2-p50 

p50[Dmn]

bait

GFP tag

Lis-1 

Lis1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

GFP-tagged proteins were pulled down using GBP (GFP-binding protein).

(Dix et al., 2013)

In ovary extract, the interaction of Dmn with Lis-1 is observed only upon overexpression of Lis-1. By contrast, in embryo extract, GFP-tagged Dmn interacts with endogenous Lis-1.

(Dix et al., 2013)

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Dix et al., 2013)
FBrf0222317-48.PD.WB
Reference
Dix et al., 2013
Description
physical association
Assay
Collection
Source/Stage
ovary / adult stagefemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
DCTN2-p50 

p50[Dmn]

bait

GFP tag

Lis-1 

Lis1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

GFP-tagged proteins were pulled down using GBP (GFP-binding protein).

(Dix et al., 2013)

Source was adult female ovary of transgenic fly line; bait produced from tagged transgenic construct; prey produced from transgenic construct.

(Dix et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)