FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000100937
Interaction Network
Interactions Browser links
erm network
Snr1 network
Reported Interactions
FBrf0224411-5.PD.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
erm 

Erm

bait

MBP tag

erm 
erm 
Snr1 

Snr1

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
erm 
N-terminal domain
sufficient binding region
aa 1-441
erm 
C-terminal domain
sufficient binding region
aa 332-611

very weak binding

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from transfected cell line extract.

Snr1 binds strongly to the N-terminal half of erm, but only very weakly to the C-terminal half of erm.

FBrf0224411-7.coIP.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
erm 

Erm

bait

FLAG tag

erm 
Snr1 

Snr1

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
erm 
N-terminal domain
sufficient binding region
aa 1-441
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

FBrf0224411-8.coIP.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Snr1 

Snr1

bait

Myc tag

erm 

Erm

prey

FLAG tag

erm 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
erm 
N-terminal domain
sufficient binding region
aa 1-441
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)