FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
wisp, Tl
FlyBase ID
FBig0000101017
Interaction Network
Interactions Browser links
wisp network
Tl network
Reported Interactions
FBrf0223050-3.coIP.PCR
Reference
Cui et al., 2013
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 1embryonic stage 2
Cell line used
Participants
Corresponds to
Reported as
Role
Note
wisp 

WISP

bait
Tl 

Toll

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Cui et al., 2013)

Lysates were fixed before wisp immunoprecipitation.

(Cui et al., 2013)
FBrf0238454-1.coIP.PCR
Reference
Coll et al., 2018
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
wisp 

Wispy

bait
Tl 

Toll

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was wild-type embryos; bait produced from endogenous gene; prey produced from endogenous gene.

(Coll et al., 2018)
FBrf0238454-2.CH.MS
Reference
Coll et al., 2018
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Tl 

Toll

bait

biotin label

Tl 
wisp 

Wispy

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Tl 
polyadenylation region
sufficient binding region
unspecified

86nt fragment

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced and labeled by in vitro transcription; prey derived from wild-type embryo extract.

(Coll et al., 2018)
FBrf0238454-4.CH.WB
Reference
Coll et al., 2018
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Tl 

Toll

bait

biotin label

Tl 
wisp 

Wispy

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Tl 
polyadenylation region
sufficient binding region
unspecified

86nt fragment

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced and labeled by in vitro transcription; prey derived from wild-type embryo extract.

(Coll et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)