FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Opa1, Mitofilin
FlyBase ID
FBig0000103043
Interaction Network
Interactions Browser links
Opa1 network
Mitofilin network
Reported Interactions
FBrf0226194-1.coIP.MS
Reference
Banerjee and Chinthapalli, 2014
Description
physical association
Assay
Collection
Source/Stage
organism / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Opa1 

Opa1-like

bait
Mitofilin 

dMitofilin

prey

18 unique peptides identified, 44% sequence coverage

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval mitochondria of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Banerjee and Chinthapalli, 2014)
FBrf0226194-10.coIP.WB
Reference
Banerjee and Chinthapalli, 2014
Description
physical association
Assay
Collection
Source/Stage
organism / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Opa1 

OPA1

bait
Mitofilin 

Mitofilin

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval mitochondria of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Banerjee and Chinthapalli, 2014)

Depletion of mitochondrial ATP by the ATPase inhibitor oligomycin increases the observed strength of the interaction.

(Banerjee and Chinthapalli, 2014)
FBrf0226194-11.coIP.WB
Reference
Banerjee and Chinthapalli, 2014
Description
physical association
Assay
Collection
Source/Stage
organism / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Mitofilin 

Mitofilin

bait
Opa1 

OPA1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval mitochondria of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Banerjee and Chinthapalli, 2014)

Depletion of mitochondrial ATP by the ATPase inhibitor oligomycin increases the observed strength of the interaction.

(Banerjee and Chinthapalli, 2014)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)