FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Dcr-2
FlyBase ID
FBig0000103981
Interaction Network
Interactions Browser links
Dcr-2 network
Reported Interactions
FBrf0229521-6.coIP.WB
Reference
Liang et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
Dcr-2 

Dcr-2

bait

GFP tag

Dcr-2 

Dcr-2

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Liang et al., 2015)
FBrf0257352-7.EM
Reference
Deng et al., 2023
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dcr-2 

DmDcr-2

self
Dcr-2 

DmDcr-2

self
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins produced as recombinant fusion proteins in a baculovirus and insect cell system.

(Deng et al., 2023)

Higher order complexes consisting of multiple Dcr-2 and r2d2 proteins, in addition to loqs bound to dsRNA, curated as a series of binary protein-protein interactions.

(Deng et al., 2023)
External Crossreferences and Linkouts ( 0 )
References (2)