FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
tld, sog
FlyBase ID
FBig0000104011
Interaction Network
Interactions Browser links
tld network
sog network
Reported Interactions
FBrf0099382-1.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tld 

Tld

enzyme

HA tag

tld 

Tld

enzyme

HA tag

sog 

Sog

enzyme target

Myc tag

sog 

Sog

enzyme target

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0127408-1.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tld 

Tld

enzyme

HA tag

tld 

Tld

enzyme

HA tag

sog 

Sog

enzyme target

Myc tag

sog 

Sog

enzyme target

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0162076-1.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tld 

Tld

enzyme

HA tag

tld 

Tld

enzyme

HA tag

sog 

Sog

enzyme target

Myc tag

sog 

Sog

enzyme target

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0183778-8.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tld 

Tld

enzyme

HA tag

tld 

Tld

enzyme

HA tag

sog 

Sog

enzyme target

Myc tag

sog 

Sog

enzyme target

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0214661-2.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tld 

tld

enzyme

HA tag

tld 

tld

enzyme

HA tag

sog 

sog

enzyme target

Myc

sog 

sog

enzyme target

Myc

sog 
sog 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0227457-1.coIP.WB
Reference
Winstanley et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
sog 

Sog

bait

Myc

tld 

Tld

prey

HA

tld 
tld 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
tld 
CUB4 domain
mutation disrupting interaction

Deletion of the CUB4 domain inhibits interaction.

tld 
CUB5 domain
mutation disrupting interaction

Deletion of the CUB5 domain inhibits interaction.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2R+ cell line; bait produced from transfected construct; prey produced from transfected construct.

(Winstanley et al., 2015)

Deletion tld CUB4 or CUB5 domain inhibits the interaction.

(Winstanley et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (6)