FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
shrb, mop
FlyBase ID
FBig0000104101
Interaction Network
Interactions Browser links
shrb network
mop network
Reported Interactions
FBrf0230887-1.Y2H
Reference
Loncle et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
shrb 

Shrub

bait

fused to GAL4 DNA-binding domain

mop 

mop

prey

fused to VP16 activation domain

mop 
mop 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mop 
Bro domain
sufficient binding region
aa 1-389
mop 
Bro domain residues I201 and V205
mutation disrupting interaction
aa 201-205

I201D, V205D

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Two-hybrid system: yeast GAL4-BD/VP16-AD

(Loncle et al., 2015)

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Loncle et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)