Vps32, ESCRT-III, vps32/snf7
vacuolar sorting protein - required for ndosomal orting omplexes equired for ransport (ESCRT) machinery - ESCRT III component - regulation of dendritic branching - completion of membrane abscission during female germline stem cell division
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\shrb using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\shrb in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Vps32 CG8055
Mutants show aberrant endosome morphology, fail to degrade ubiquitinated cargoes, and a degree of endosomal accumulation of the signaling receptors.
dsRNA made from templates generated with primers directed against Vps32 that is transfected into S2 treated with Listeria monocytogenes reveals Vps32 to be involved in Listeria monocytogenes entry, intracellular growth, and vacuolar escape.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Area matching Drosophila EST AA264253. This EST has sequence similarity to SNF7 genes.