FlyBase Allele Report: Dmel\shrb[GFP.KI]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\shrb^GFP.KI

General Information

Symbol

Dmel\shrb^GFP.KI

Species

D. melanogaster

Name

FlyBase ID

FBal0374958

Feature type

allele

Associated gene

Associated Insertion(s)

TI{TI}shrb^GFP.KI

Carried in Construct

Also Known As

Shrub::GFP

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

(Mathieu et al., 2022)

gene targeting by homologous recombination

(Mathieu et al., 2022)

cre recombinase

(Mathieu et al., 2022)

Progenitor genotype

Associated Insertion(s)

TI{TI}shrb^GFP.KI

Cytology

Description

GFP is inserted at the N-terminal of endogenous shrb.

(Mathieu et al., 2022)

Allele components

Component

Use(s)

Tagged with

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal meiotic cell cycle | oogenesis

(Bruelle et al., 2023)

abnormal mitotic cell cycle | P-stage

(Bruelle et al., 2023)

Phenotype Manifest In

external sensory organ precursor cell | P-stage

(Bruelle et al., 2023)

female germline stem cell

(Bruelle et al., 2023)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

shrb^GFP.KI has abnormal mitotic cell cycle | P-stage phenotype, suppressible by cora^GD1405/Scer\GAL4^pnr.PU

(Bruelle et al., 2023)

NOT Enhancer of

Statement

Reference

shrb^GFP.KI is a non-enhancer of abnormal mitotic cell cycle | P-stage phenotype of Scer\GAL4^pnr.PU, cora^GD1405

(Bruelle et al., 2023)

NOT Suppressor of

Statement

Reference

shrb^GFP.KI is a non-suppressor of abnormal mitotic cell cycle | P-stage phenotype of Scer\GAL4^pnr.PU, cora^GD1405

(Bruelle et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

shrb^GFP.KI has external sensory organ precursor cell | P-stage phenotype, suppressible by cora^GD1405/Scer\GAL4^pnr.PU

(Bruelle et al., 2023)

NOT Enhancer of

Statement

Reference

shrb^GFP.KI is a non-enhancer of external sensory organ precursor cell | P-stage phenotype of Scer\GAL4^pnr.PU, cora^GD1405

(Bruelle et al., 2023)

NOT Suppressor of

Statement

Reference

shrb^GFP.KI is a non-suppressor of external sensory organ precursor cell | P-stage phenotype of Scer\GAL4^pnr.PU, cora^GD1405

(Bruelle et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

shrb^GFP.KI

shrb^KI

(Mathieu et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections