FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000104164
Interaction Network
Interactions Browser links
r2d2 network
Reported Interactions
FBrf0229521-5.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
r2d2 

R2D2

bait

GFP tag

r2d2 

R2D2

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

FBrf0257352-8.EM
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
r2d2 

R2D2

neutral component
r2d2 

R2D2

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Higher order complexes consisting of multiple Dcr-2 and r2d2 proteins, in addition to loqs bound to dsRNA, curated as a series of binary protein-protein interactions.

Interaction in vitro; proteins produced as recombinant fusion proteins in a baculovirus and insect cell system.

External Crossreferences and Linkouts ( 0 )
References (2)