FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
thoc5, cuff
FlyBase ID
FBig0000104212
Interaction Network
Interactions Browser links
thoc5 network
cuff network
Reported Interactions
FBrf0231583-2.coIP.WB
Reference
Hur et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
thoc5 

Thoc5

bait

FLAG tag

cuff 

Cuff

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

At least some of the thoc5-cuff interaction is RNA-independent (only partially affected by RNase). thoc5 interacts with cuff but not its paralog CG9125, or with rhi.

(Hur et al., 2016)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Hur et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)