FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Miro, Marf
FlyBase ID
FBig0000104240
Interaction Network
Interactions Browser links
Miro network
Marf network
Reported Interactions
FBrf0232092-3.coIP.WB
Reference
Lee et al., 2016
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Miro 

dMiro

bait

Myc tag

Miro 
Miro 
Marf 

Marf

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Miro 
phosphorylation site S66
mutation increasing interaction
aa 66

S66E

Miro 
phosphorylation site S66
mutation decreasing interaction
aa 66

S66A

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Lee et al., 2016)

Mutations that mimic Ser66 phosphorylation of Miro increase the intearction with porin and Marf. A phosphomimetic mutant of Miro (S66E) exhibits greater GTPase activity than wild-type.

(Lee et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)