FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mir-184, Nrx-IV
FlyBase ID
FBig0000104349
Interaction Network
Interactions Browser links
mir-184 network
Nrx-IV network
Reported Interactions
FBrf0208499-8.miR-mRNA.LUC
Reference
Iovino et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mir-184 

mir-184

bait
Nrx-IV 

Nrx-IV

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from endogenous gene; prey produced from transfected reporter construct.

(Iovino et al., 2009)

luciferase reporter assay

(Iovino et al., 2009)
FBrf0216115-10.miR-mRNA.LUC
Reference
Kertesz et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mir-184 

miR-184

bait
Nrx-IV 

Nrx

prey
Nrx-IV 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Nrx-IV 
3-prime UTR
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

(Kertesz et al., 2007)

Luciferase reporter assay.

(Kertesz et al., 2007)
FBrf0231586-2.miR-mRNA.IHC
Reference
Sharifkhodaei et al., 2016
Description
physical association
Assay
Collection
Source/Stage
wing disc / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-184 

mir-184

bait
Nrx-IV 

Nrx-IV

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval wing discs of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Sharifkhodaei et al., 2016)

Overexpression of mir-184 reduces Nrx-IV protein levels.

(Sharifkhodaei et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)