FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
tkv, S6KL
FlyBase ID
FBig0000104391
Interaction Network
Interactions Browser links
tkv network
S6KL network
Reported Interactions
FBrf0227746-1.coIP.WB
Reference
Zhao et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
tkv 

tkv

bait

Myc tag

S6KL 

S6KL

prey

Flag tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cells; bait produced from tagged transfected construct; prey produced from tagged transfected construct.

(Zhao et al., 2015)

The kinase dead K193Q mutant of S6KL does not affect the interaction between S6KL and tkv.

(Zhao et al., 2015)
FBrf0232477-4.coIP.WB
Reference
Li et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
tkv 

Tkv

bait

Myc tag

S6KL 

S6KL

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

tkv, Ube3a and S6KL were co-transfected, then immunoprecipitated sequentially by Myc then HA tags.

(Li et al., 2016)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Li et al., 2016)
FBrf0232477-5.coIP.WB
Reference
Li et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
S6KL 

S6KL

bait

HA tag

tkv 

Tkv

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

tkv, Ube3a and S6KL were co-transfected, then immunoprecipitated sequentially by Myc then HA tags.

(Li et al., 2016)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Li et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)