FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
dsh, pk
FlyBase ID
FBig0000104392
Interaction Network
Interactions Browser links
dsh network
pk network
Reported Interactions
FBrf0148922-1.PD.A
Reference
Tree et al., 2002
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dsh 

Dsh

bait

GST tag

dsh 
pk 

Pksple

prey

[35]S label

pk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dsh 
DEP domain
sufficient binding region
aa 3940623

"G12" construct

pk 
PET and LIM domains
sufficient binding region
aa 516-809

"PETLIM" construct

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Tree et al., 2002)
FBrf0188147-6.PD.A
Reference
Jenny et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dsh 

Dsh

bait

GST tag

dsh 
pk 

Pk

prey

[35]S label

pk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dsh 
bPDZ domain
sufficient binding region
aa 200-357
pk 
PET and LIM domains
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Jenny et al., 2005)

Binding of pk to GST-dsh is inhibited by addition of His-tagged dgo, suggesting competitive binding to the dsh bPDZ domain.

(Jenny et al., 2005)
FBrf0231241-5.PD.A
Reference
Dollar et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dsh 

Dsh

bait

GST tag

dsh 
pk 

Pk

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dsh 
bPDZ domain
sufficient binding region
aa 200-357
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Positive control.

(Dollar et al., 2016)

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Dollar et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)