FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
l(2)gl
FlyBase ID
FBig0000104471
Interaction Network
Interactions Browser links
l(2)gl network
Reported Interactions
FBrf0183828-3.coIP.WB
Reference
Betschinger et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
l(2)gl 

Lgl

bait
l(2)gl 

Lgl

prey

MYC tag

l(2)gl 
l(2)gl 
l(2)gl 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
l(2)gl 
N terminus
sufficient binding region
aa 1-640

coordinates relative to l(2)gl-PA

l(2)gl 
C terminus
sufficient binding region
aa 769-1161

coordinates relative to l(2)gl-PA

l(2)gl 
aPKC phosphorylation sites
mutation disrupting interaction
aa 656-664

S656A, S660A and S664A, coordinates relative to l(2)gl-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Betschinger et al., 2005)

An antibody directed at the N terminal region of l(2)gl was used in this experiment to co-precipitate the other region of l(2)gl.

(Betschinger et al., 2005)
External Crossreferences and Linkouts ( 0 )
References (1)