FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mir-184, ttk
FlyBase ID
FBig0000104536
Interaction Network
Interactions Browser links
mir-184 network
ttk network
Reported Interactions
FBrf0208499-24.miR-mRNA.LUC
Reference
Iovino et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mir-184 

mir-184

bait
mir-184 
ttk 

ttk

prey
ttk 
ttk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
ttk 
3-prime UTR
sufficient binding region
ttk 
mir-184 target site
necessary binding region
UAUUAAUUCUAACACUUGCUCCGUCCA

seed: UCCGUCCA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

luciferase reporter assay

(Iovino et al., 2009)

Source was S2 cell line; bait produced from endogenous gene; prey produced from transfected reporter construct.

(Iovino et al., 2009)
FBrf0208499-25.miR-mRNA.WB
Reference
Iovino et al., 2009
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 1embryonic stage 2
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-184 

mir-184

bait
ttk 

ttk

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Levels of ttk protein are elevated in mir-184 mutant background.

(Iovino et al., 2009)

Source was embryos; bait produced from endogenous gene; prey produced from endogenous gene.

(Iovino et al., 2009)
FBrf0216115-8.miR-mRNA.LUC
Reference
Kertesz et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mir-184 

miR-184

bait
ttk 

ttk

prey
ttk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
ttk 
3-prime UTR
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

(Kertesz et al., 2007)

Luciferase reporter assay.

(Kertesz et al., 2007)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)