FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
corto, Trl
FlyBase ID
FBig0000105052
Interaction Network
Interactions Browser links
corto network
Trl network
Reported Interactions
FBrf0160909-13.PD.A
Reference
Salvaing et al., 2003
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
corto 

Corto

bait

GST tag

corto 
Trl 

GAGA

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
corto 
Chromo domain
sufficient binding region
aa 127-203
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Salvaing et al., 2003)
FBrf0160909-14.Y2H
Reference
Salvaing et al., 2003
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
corto 

Corto

bait

fused to LexA DNA-binding domain

corto 
Trl 

GAGA

prey

fused to B42 activation domain

Trl 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
corto 
N terminal region
sufficient binding region
aa 1-324
Trl 
BTB domain
sufficient binding region
aa 34-99

coordinates relative to Trl-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Salvaing et al., 2003)

The N terminal half of corto interacts with the BTB domain of Trl.

(Salvaing et al., 2003)

Two-hybrid system: yeast LexA-BD/B42-AD

(Salvaing et al., 2003)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)