FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Chrac-14, Top2
FlyBase ID
FBig0000105203
Interaction Network
Interactions Browser links
Chrac-14 network
Top2 network
Reported Interactions
FBrf0129776-10.coIP.WB
Reference
Corona et al., 2000
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 15embryonic stage 16
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Chrac-14 

CHRAC-14

bait
Top2 

Topo II

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryonic nuclear extract of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Corona et al., 2000)

Given that only a small fraction of Top2 coimmunoprecipitates with Chrac-14, and that Top2 can be chromatographically separated from Chrac-14, Top2 is not considered a diagnositic subunit of the CHRAC complex.

(Corona et al., 2000)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)