FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mir-92a, jigr1
FlyBase ID
FBig0000105455
Interaction Network
Interactions Browser links
mir-92a network
jigr1 network
Reported Interactions
FBrf0228546-1.miR-mRNA.PCR
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
larval brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-92a 

mir-92a

bait
jigr1 

jigr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval brains of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yuva-Aydemir et al., 2015)

Mutation of mir-92a increases jigr1 mRNA levels, while overexpression of mir-92a reduces jigr1 mRNA levels.

(Yuva-Aydemir et al., 2015)
FBrf0228546-3.miR-mRNA.WB
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
larval brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-92a 

mir-92a

bait
jigr1 

jigr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval brains of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yuva-Aydemir et al., 2015)

Mutation of mir-92a increases jigr1 protein levels, while overexpression of mir-92a reduces jigr1 protein levels.

(Yuva-Aydemir et al., 2015)
FBrf0228546-5.miR-mRNA.IHC
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
larval brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-92a 

mir-92a

bait
jigr1 

jigr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval brains of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yuva-Aydemir et al., 2015)

Mutation of mir-92a increases jigr1 protein levels in neuroblasts.

(Yuva-Aydemir et al., 2015)
FBrf0228546-7.miR-mRNA.LUC
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mir-92a 

mir-92a

bait
jigr1 

jigr1

prey
jigr1 
jigr1 
jigr1 
jigr1 
jigr1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
jigr1 
long 3-prime UTR
sufficient binding region
jigr1 
5-prime UTR
sufficient binding region
jigr1 
mir-92a 3-UTR target site 1
necessary binding region
AUGCAAUG
jigr1 
mir-92a 3-UTR target site 2
necessary binding region
UGUGCGUUG
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

(Yuva-Aydemir et al., 2015)

Luciferase reporter assay.

(Yuva-Aydemir et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)