FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mir-92b, jigr1
FlyBase ID
FBig0000105477
Interaction Network
Interactions Browser links
mir-92b network
jigr1 network
Reported Interactions
FBrf0228546-2.miR-mRNA.PCR
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
larval brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-92b 

mir-92b

bait
jigr1 

jigr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval brains of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yuva-Aydemir et al., 2015)

Mutation of mir-92b increases jigr1 mRNA levels, while overexpression of mir-92b reduces jigr1 mRNA levels.

(Yuva-Aydemir et al., 2015)
FBrf0228546-4.miR-mRNA.WB
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
larval brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-92b 

mir-92b

bait
jigr1 

jigr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval brains of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yuva-Aydemir et al., 2015)

Mutation of mir-92b increases jigr1 protein levels, while overexpression of mir-92b reduces jigr1 protein levels.

(Yuva-Aydemir et al., 2015)
FBrf0228546-6.miR-mRNA.IHC
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
larval brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-92b 

mir-92b

bait
jigr1 

jigr1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval brains of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Yuva-Aydemir et al., 2015)

Mutation of mir-92b increases jigr1 protein levels in neuroblasts.

(Yuva-Aydemir et al., 2015)
FBrf0228546-8.miR-mRNA.LUC
Reference
Yuva-Aydemir et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mir-92b 

mir-92b

bait
jigr1 

jigr1

prey
jigr1 
jigr1 
jigr1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
jigr1 
long 3-prime UTR
sufficient binding region
jigr1 
5-prime UTR
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

(Yuva-Aydemir et al., 2015)

Luciferase reporter assay.

(Yuva-Aydemir et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)