FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
BicC, Not3
FlyBase ID
FBig0000105498
Interaction Network
Interactions Browser links
BicC network
Not3 network
Reported Interactions
FBrf0200435-3.PD.WB
Reference
Chicoine et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
BicC 

Bic-C

bait

MBP tag

Not3 

NOT3/5

prey

GST tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Chicoine et al., 2007)
FBrf0200435-4.PD.WB
Reference
Chicoine et al., 2007
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Not3 

NOT3/5

bait

GST tag

BicC 

Bic-C

prey

MBP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Chicoine et al., 2007)
FBrf0200435-6.coIP.WB
Reference
Chicoine et al., 2007
Description
physical association
Assay
Collection
Source/Stage
ovary / femaleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
BicC 

Bic-C

bait
Not3 

NOT3/5

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female ovaries of transgenic fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Chicoine et al., 2007)

The BicC-Not3 interaction persists after RNase treatment and is thus RNA-independent.

(Chicoine et al., 2007)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)