FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
MBD-R2, mof
FlyBase ID
FBig0000105763
Interaction Network
Interactions Browser links
MBD-R2 network
mof network
Reported Interactions
FBrf0191180-15.coIP.MS
Reference
Mendjan et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Sg4
Participants
Corresponds to
Reported as
Role
Note
mof 

MOF

bait

TAP tag

MBD-R2 

MBD-R2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of Sg4 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Mendjan et al., 2006)
FBrf0191180-28.coIP.MS
Reference
Mendjan et al., 2006
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mof 

MOF

bait

TAP tag

MBD-R2 

MBD-R2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Mendjan et al., 2006)
FBrf0191180-52.coIP.WB
Reference
Mendjan et al., 2006
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mof 

MOF

bait
MBD-R2 

MBD-R2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Mendjan et al., 2006)
FBrf0191180-58.coIP.WB
Reference
Mendjan et al., 2006
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
MBD-R2 

MBD-R2

bait
mof 

MOF

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Mendjan et al., 2006)
FBrf0191180-70.coIP.WB
Reference
Mendjan et al., 2006
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mof 

MOF

bait
MBD-R2 

MBD-R2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Mendjan et al., 2006)
FBrf0211222-31.coIP.WB
Reference
Raja et al., 2010
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
MBD-R2 

MBD-R2

bait
mof 

MOF

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Raja et al., 2010)
FBrf0241907-12.coIP.WB
Reference
Lam et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
MBD-R2 

MBD-R2

bait

FLAG tag

mof 

MOF

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of S2 cell line; bait produced from transfected construct or endogenous gene; prey produced from endogenous gene.

(Lam et al., 2019)
FBrf0264203-27.CH.WB
Reference
Lenz et al., 2025
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
MBD-R2 

MBD-R2

neutral component
MBD-R2 

MBD-R2

neutral component
MBD-R2 

MBD-R2

neutral component
mof 

mof

neutral component
mof 

mof

neutral component
mof 

mof

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins produced from endogenous gene.

(Lenz et al., 2025)

hang, nsl1, MBD-R2, Rcd5 and mof form a complex, captured as pairwise interactions.

(Lenz et al., 2025)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (4)