FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Liprin-α, unc-13
FlyBase ID
FBig0000106660
Interaction Network
Interactions Browser links
Liprin-α network
unc-13 network
Reported Interactions
FBrf0233590-3.Y2H
Reference
Böhme et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Liprin-α 

Liprin-α

bait

fused to LexA DNA-binding domain

Liprin-α 
unc-13 

Unc13B

prey

fused to GAL4 activation domain

unc-13 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
unc-13 
Unc13B N-terminal region
sufficient binding region
aa 600-1322

coordinates relative to unc-13-PB

Liprin-α 
N-terminal region
sufficient binding region
aa 1-550

coordinates relative to Liprin-α-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Böhme et al., 2016)

Two-hybrid system: yeast LexA-BD/GAL4-AD

(Böhme et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)