FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Diap2, PGRP-LC
FlyBase ID
FBig0000106861
Interaction Network
Interactions Browser links
Diap2 network
PGRP-LC network
Reported Interactions
FBrf0233515-2.coIP.WB
Reference
Neyen et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Diap2 

dIAP2

bait

HA tag

PGRP-LC 

PGRP-LC

prey

V5 tag

PGRP-LC 
PGRP-LC 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
PGRP-LC 
PHD domain
sufficient binding region
aa 1-65

"PHD" construct, coordinates relative to PGRP-LC-PE.

PGRP-LC 
PHD domain
necessary binding region
aa 1-65

"ΔPHD" construct, coordinates relative to PGRP-LC-PE.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Neyen et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)