FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mu2, Su(var)205
FlyBase ID
FBig0000108542
Interaction Network
Interactions Browser links
mu2 network
Su(var)205 network
Reported Interactions
FBrf0216284-1.Y2H
Reference
Dronamraju and Mason, 2011
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
mu2 

mu2

bait

fused to GAL4 DNA-binding domain

mu2 
Su(var)205 

Su(var)205

prey

fused to GAL4 activation domain

Su(var)205 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mu2 
interaction domain
sufficient binding region
aa 775-1025aa 900-1190
Su(var)205 
interaction domain
sufficient binding region
aa 129-207
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey from embryo or S2 cell cDNA expression library).

(Dronamraju and Mason, 2011)
FBrf0216284-2.coIP.WB
Reference
Dronamraju and Mason, 2011
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mu2 

mu2

bait

GFP tag

Su(var)205 

Su(var)205

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Dronamraju and Mason, 2011)
FBrf0216284-3.coIP.WB
Reference
Dronamraju and Mason, 2011
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Su(var)205 

Su(var)205

bait
mu2 

mu2

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from endogenous gene; prey produced from tagged transgenic construct.

(Dronamraju and Mason, 2011)
FBrf0216284-4.PD.WB
Reference
Dronamraju and Mason, 2011
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
mu2 

mu2

bait

GST tag

mu2 
Su(var)205 

Su(var)205

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mu2 
interaction domain
sufficient binding region
aa 900-1000
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type nuclear S2 cell extract.

(Dronamraju and Mason, 2011)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)