FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
chic, Imp
FlyBase ID
FBig0000108897
Interaction Network
Interactions Browser links
chic network
Imp network
Reported Interactions
FBrf0224571-1.coIP.PCR
Reference
Medioni et al., 2014
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Imp 

Imp

bait

FLAG tag

chic 

chic

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Medioni et al., 2014)

Imp protein does not bind other transcripts tested: Rho1, tsr, Arp2, Arp3, Act5C, Act42A.

(Medioni et al., 2014)
FBrf0224571-2.PD.WB
Reference
Medioni et al., 2014
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
chic 

chic

bait

biotin label

chic 
Imp 

Imp

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
chic 
3-prime UTR
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced and labeled by in vitro transcription; prey derived from wild-type adult head extract.

(Medioni et al., 2014)
FBrf0224571-3.EMSA.A
Reference
Medioni et al., 2014
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Imp 

Imp

bait

MBP tag

chic 

chic

prey

[32]P label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Medioni et al., 2014)
FBrf0243755-3.PD.WB
Reference
Genovese et al., 2019
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
chic 

chic

bait

biotin label

chic 
Imp 

Imp

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
chic 
3-prime UTR
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Positive control.

(Genovese et al., 2019)

Interaction in vitro; bait produced and labeled by in vitro transcription; prey derived from wild-type adult head extract.

(Genovese et al., 2019)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)