FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Rho1, scra
FlyBase ID
FBig0000109269
Interaction Network
Interactions Browser links
Rho1 network
scra network
Reported Interactions
FBrf0219117-1.PD.WB
Reference
Liu et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
scra 

scra

bait

GST tag

scra 
Rho1 

Rho1

prey

MBP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
scra 
AH and PH domain
sufficient binding region
aa 704-1124
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Liu et al., 2012)
FBrf0259671-1.PD.A
Reference
Stjepić et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rho1 

Rho1

bait

GST tag

scra 

Anillin

prey

[35]S label

scra 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
scra 
RBD domain
sufficient binding region
aa 748-1239

coordinates relative to scra-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Stjepić et al., 2024)

Binding of scra can occur with GTP or GDP loaded Rho1.

(Stjepić et al., 2024)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)