FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
nw
FlyBase ID
FBig0000109418
Interaction Network
Interactions Browser links
nw network
Reported Interactions
FBrf0229268-1.CM.MW
Reference
Ray et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
nw 

nw

self

FLAG tag

nw 

nw

self

FLAG tag

nw 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
nw 
C-type lectin domain
mutation disrupting interaction
aa 179

C179A, corresponds to nw-PA, described by author as 5th CTLD Cys, position inferred by curator.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was live S2 cells; proteins produced from transfected constructs.

(Ray et al., 2015)

Both long and short nw isoforms, corresponding to nw-PC and nw-PA, form homo- and heterodimers.

(Ray et al., 2015)
FBrf0229268-2.coIP.WB
Reference
Ray et al., 2015
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
nw 

nw

bait

FLAG tag

nw 

nw

prey

HA tag

nw 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
nw 
C-type lectin domain
mutation disrupting interaction
aa 179

C179A, corresponds to nw-PA, described by author as 5th CTLD Cys, position inferred by curator.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Ray et al., 2015)
External Crossreferences and Linkouts ( 0 )
References (1)