FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000110460
Interaction Network
Interactions Browser links
mir-980 network
Rbfox1 network
Reported Interactions
FBrf0231056-1.miR-mRNA.IHC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-980

bait

Rbfox1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was heads of transgenic fly line; bait produced from endogenous gene; prey produced from endogenous gene.

Overexpression of mir-980 sponge increases Rbfox1 protein levels.

FBrf0231056-2.miR-mRNA.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-980

bait

Rbfox1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was heads of transgenic fly line; bait produced from endogenous gene; prey produced from endogenous gene.

Overexpression of mir-980 sponge increases Rbfox1 protein levels.

FBrf0231056-3.miR-mRNA.IHC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-980

bait

Rbfox1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was heads of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

Overexpression of mir-980 reduces Rbfox1 protein levels.

FBrf0237915-1.miR-mRNA.LUC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

miR-980

bait

Rbfox1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
3-prime UTR
sufficient binding region
nt 4613-4993nt 6123-6518

coordinates relative to Rbfox1-RH

coordinates relative to Rbfox1-RH

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Luciferase reporter assay.

Source was S2R+ cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

FBrf0237915-2.miR-mRNA.PCR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

miR-980

bait

Rbfox1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult ovaries of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

Loss of mir-980 increases Rbfox1 mRNA levels.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)