FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000115121
Interaction Network
Interactions Browser links
Dek network
His3 network
Reported Interactions
FBrf0209754-13.AF.MS
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dek 

dDEK

bait

FLAG tag

His3 

H3

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was chromatin fraction of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

FBrf0209754-17.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dek 

dDEK

bait

FLAG tag

His3 

H3

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was chromatin fraction of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

FBrf0209754-21.PD.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dek 

dDEK

bait

S tag

His3 

H3

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey purified from S2 cell chromatin fraction.

K4me2 and K4me3 methylated forms of His3 were detected associated with Dek.

FBrf0209754-22.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dek 

dDEK

bait

FLAG tag

His3 

H3

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was chromatin fraction of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

Dek binds more strongly to His3.3 than to His3.

External Crossreferences and Linkouts ( 0 )
References (1)