FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mle, RpS29
FlyBase ID
FBig0000115922
Interaction Network
Interactions Browser links
mle network
RpS29 network
Reported Interactions
FBrf0237085-2.CL.SEQ
Reference
Ilik et al., 2017
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
mle 

MLE

bait

HBH tag

mle 
RpS29 

Rps29

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mle 
helicase domain residues 413
mutation increasing interaction
aa 413

K413E, coordinates relative to mle-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Ilik et al., 2017)
FBrf0246226-14.coIP.SEQ
Reference
Müller et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
mle 

MLE

bait
RpS29 

RpS29:roX2

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of a male S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Müller et al., 2020)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)