FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
shn, Sin3A
FlyBase ID
FBig0000115942
Interaction Network
Interactions Browser links
shn network
Sin3A network
Reported Interactions
FBrf0207974-2.coIP.WB
Reference
Cai and Laughon, 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
shn 

Shn

bait

FLAG tag

shn 
shn 
Sin3A 

dSin3A

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
shn 
C-terminal domain
sufficient binding region
aa 1888-2527

coordinates relative to a 2527aa isoform

shn 
RD6 domain
mutation disrupting interaction
aa 1896,1897

P1896A,P1897A, coordinates mapped to shn-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Cai and Laughon, 2009)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)