FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Syx17, Ykt6
FlyBase ID
FBig0000116610
Interaction Network
Interactions Browser links
Syx17 network
Ykt6 network
Reported Interactions
FBrf0238842-2.coIP.WB
Reference
Takáts et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Syx17 

Syx17

bait

FLAG tag

Ykt6 

Ykt6

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Co-expression of Vamp7 competes with Ykt6 for binding to Syx17

(Takáts et al., 2018)

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Takáts et al., 2018)
FBrf0238842-6.PD.MW
Reference
Takáts et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Syx17 

Syx17

bait

GST tag

Syx17 
Ykt6 

Ykt6

prey

MBP tag

Ykt6 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Syx17 
SNARE domain
sufficient binding region
unspecified
Ykt6 
SNARE domain
sufficient binding region
unspecified
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Takáts et al., 2018)
FBrf0238842-7.PD.WB
Reference
Takáts et al., 2018
Description
physical association
Assay
Collection
Source/Stage
organism / larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Ykt6 

Ykt6

bait

GST tag

Syx17 

Syx17

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type larval extract.

(Takáts et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)