FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Art1, mre11
FlyBase ID
FBig0000116654
Interaction Network
Interactions Browser links
Art1 network
mre11 network
Reported Interactions
FBrf0239054-1.ENZ.A
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Art1 

DART1

enzyme

His tag

Art1 

DART1

enzyme

His tag

mre11 

Mre11

enzyme target

MBP tag, H[3] label

mre11 

Mre11

enzyme target

MBP tag, H[3] label

mre11 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0239054-2.coIP.WB
Reference
Yuan et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Art1 

DART1

bait

V5 tag

mre11 

Mre11

prey

Myc tag

mre11 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mre11 
interaction domain
sufficient binding region
aa 1-554,584-620

GAR domain deleted

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Yuan et al., 2018)
FBrf0239054-3.coIP.WB
Reference
Yuan et al., 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
mre11 

Mre11

bait

Myc tag

mre11 
Art1 

DART1

prey

V5 tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
mre11 
interaction domain
sufficient binding region
aa 1-554,584-620

GAR domain deleted

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Yuan et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)