FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
dome, Eb1
FlyBase ID
FBig0000116661
Interaction Network
Interactions Browser links
dome network
Eb1 network
Reported Interactions
FBrf0238664-5.coIP.WB
Reference
Chen et al., 2018
Description
physical association
Assay
Collection
Source/Stage
testis / maleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dome 

Dome

bait

GFP tag

Eb1 

EB1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was GSC-enriched testes of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Chen et al., 2018)
FBrf0238664-6.PD.WB
Reference
Chen et al., 2018
Description
physical association
Assay
Collection
Source/Stage
testis / maleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
dome 

Dome

bait

His tag

dome 
Eb1 

EB1

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
dome 
SxIP domain
necessary binding region
aa 1107-1110

deletion of SQIP, coordinates relative to dome-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from extract of GSC-enriched testes of transgenic fly line.

(Chen et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)