FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Hsap\MAPT, 14-3-3ζ
FlyBase ID
FBig0000116678
Interaction Network
Interactions Browser links
Hsap\MAPT network
14-3-3ζ network
Reported Interactions
FBrf0239248-1.coIP.WB
Reference
Papanikolopoulou et al., 2018
Description
physical association
Assay
Collection
Source/Stage
head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Hsap\MAPT 

TAU

bait

FLAG tag

14-3-3ζ 

LEO

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Papanikolopoulou et al., 2018)
FBrf0239248-3.AF.WB
Reference
Papanikolopoulou et al., 2018
Description
physical association
Assay
Collection
Source/Stage
head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
14-3-3ζ 

LEO

bait
Hsap\MAPT 

TAU

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

GST-difopein-conjugated beads were used to pull down 14-3-3 proteins from fly head lysates. Co-purifying Hsap\MAPT was detected by western blot.

(Papanikolopoulou et al., 2018)

Source was adult heads of transgenic fly line; bait produced from endogenous gene; prey produced from transgenic construct.

(Papanikolopoulou et al., 2018)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)